Structure-function studies of human aromatase by site-directed mutagenesis: kinetic properties of mutants Pro-308----Phe, Tyr-361----Phe, Tyr-361----Leu, and Phe-406----Arg.
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Structural basis for androgen specificity and oestrogen synthesis in human aromataseStructural Basis for the Functional Roles of Critical Residues in Human Cytochrome P450 AromataseMolecular basis of the inhibition of human aromatase (estrogen synthetase) by flavone and isoflavone phytoestrogens: A site-directed mutagenesis studyAromatase deficiency in a Chinese adult man caused by novel compound heterozygous CYP19A1 mutations: effects of estrogen replacement therapy on the bone, lipid, liver and glucose metabolism.X-ray structure of human aromatase reveals an androgen-specific active siteTunable recognition of the steroid alpha-face by adjacent pi-electron density.Aromatase inhibitors: clinical pharmacology and therapeutic implications in breast cancer.Inhibitors of aromatase prevent degradation of the enzyme in cultured human tumour cells.Enantioselectivity of some 1-[(benzofuran-2-yl) phenylmethyl] imidazoles as aromatase (P450AROM) inhibitors.
P2860
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P2860
Structure-function studies of human aromatase by site-directed mutagenesis: kinetic properties of mutants Pro-308----Phe, Tyr-361----Phe, Tyr-361----Leu, and Phe-406----Arg.
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Structure-function studies of ...... 61----Leu, and Phe-406----Arg.
@en
Structure-function studies of ...... 61----Leu, and Phe-406----Arg.
@nl
type
label
Structure-function studies of ...... 61----Leu, and Phe-406----Arg.
@en
Structure-function studies of ...... 61----Leu, and Phe-406----Arg.
@nl
prefLabel
Structure-function studies of ...... 61----Leu, and Phe-406----Arg.
@en
Structure-function studies of ...... 61----Leu, and Phe-406----Arg.
@nl
P2093
P2860
P356
P1476
Structure-function studies of ...... 61----Leu, and Phe-406----Arg.
@en
P2093
P2860
P304
P356
10.1073/PNAS.88.2.410
P407
P577
1991-01-01T00:00:00Z