about
1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitorsCJ-1639: A Potent and Highly Selective Dopamine D3 Receptor Full AgonistDelivery and tracking of quantum dot peptide bioconjugates in an intact developing avian brainResonance Energy Transfer Between Luminescent Quantum Dots and Diverse Fluorescent Protein AcceptorsOptimizing protein coordination to quantum dots with designer peptidyl linkers.Conformationally constrained analogues of diacylglycerol. 29. Cells sort diacylglycerol-lactone chemical zip codes to produce diverse and selective biological activitiesProbing the Quenching of Quantum Dot Photoluminescence by Peptide-Labeled Ruthenium(II) Complexes.Probes for narcotic receptor mediated phenomena. 40. N-substituted cis-4a-ethyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-8-olsSynthesis of enantiopure 10-nornaltrexones in the search for Toll-like receptor 4 antagonists and opioid ligandsX-ray crystallography of chemical compounds.Chiral Resolution and Serendipitous Fluorination Reaction for the Selective Dopamine D3 Receptor Antagonist BAK2-66Identification of neuropeptide S antagonists: structure-activity relationship studies, X-ray crystallography, and in vivo evaluation.Synthesis and immunological effects of heroin vaccinesCrystal structure of biphalin sulfate: a multireceptor opioid peptide.Growth and development of the barnacle Amphibalanus amphitrite: time and spatially resolved structure and chemistry of the base plate.Direct reaction of amides with nitric oxide to form diazeniumdiolates.Peripheral cannabinoid-1 receptor inverse agonism reduces obesity by reversing leptin resistance.Synthesis of salvinorin A analogues as opioid receptor probes.Enantiospecific Allosteric Modulation of Cannabinoid 1 Receptor.Using click chemistry toward novel 1,2,3-triazole-linked dopamine D3 receptor ligands.Efficacy, but not antibody titer or affinity, of a heroin hapten conjugate vaccine correlates with increasing hapten densities on tetanus toxoid, but not on CRM197 carriersReversal of pancreatitis-induced pain by an orally available, small molecule interleukin-6 receptor antagonistStructural Basis of Species-Dependent Differential Affinity of 6-Alkoxy-5-Aryl-3-Pyridinecarboxamide Cannabinoid-1 Receptor Antagonists.A fluorescence resonance energy transfer-derived structure of a quantum dot-protein bioconjugate nanoassemblyInvestigation of Zr(IV) and 89Zr(IV) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging.Synthesis and pharmacological effects of the enantiomers of the N-phenethyl analogues of the ortho and para e- and f-oxide-bridged phenylmorphans.PROBES FOR NARCOTIC RECEPTOR MEDIATED PHENOMENA. 38. AN EXPEDITIOUS SYNTHESIS OF RAC-CIS-4a-ETHYL-2-METHYL-1,2,3,4,4a,9a-HEXAHYDROBENZOFURO[2,3-c]PYRIDIN-6-OL AND RAC-CIS-2-METHYL-4a-PHENETHYL-1,2,3,4,4a,9a-HEXAHYDROBENZOFURO[2,3-c]PYRIDIN-6-OLThe role of crystallography in drug designA novel series of piperidin-4-yl-1,3-dihydroindol-2-ones as agonist and antagonist ligands at the nociceptin receptor.Design and synthesis of novel antimicrobials with activity against Gram-positive bacteria and mycobacterial species, including M. tuberculosis.Selecting improved peptidyl motifs for cytosolic delivery of disparate protein and nanoparticle materials.Expeditious synthesis, enantiomeric resolution, and enantiomer functional characterization of (4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide (4BP-TQS): an allosteric agonist-positive allosteric modulator of α7 nicotiStereospecific total synthesis of the indole alkaloid ervincidine. Establishment of the C-6 hydroxyl stereochemistry.Integrated metagenomic and metaproteomic analyses of marine biofilm communities.Nature-inspired stereospecific total synthesis of P-(+)-dispegatrine and four other monomeric sarpagine indole alkaloids.Extraction of Perchlorate Using Porous Organosilicate Materials.Discovery of a novel small molecule agonist scaffold for the APJ receptor.PABA/NO lead optimization: Improved targeting of cytotoxicity to glutathione S-transferase P1-overexpressing cancer cells.Detection of explosives in a dynamic marine environment using a moored TNT immunosensor.North- and south-bicyclo[3.1.0]hexene nucleosides: the effect of ring planarity on anti-HIV activity.
P50
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P50
description
hulumtues
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researcher
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wetenschapper
@nl
հետազոտող
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name
Jeffrey R Deschamps
@nl
Jeffrey R Deschamps
@sl
Jeffrey R. Deschamps
@en
Jeffrey R. Deschamps
@es
type
label
Jeffrey R Deschamps
@nl
Jeffrey R Deschamps
@sl
Jeffrey R. Deschamps
@en
Jeffrey R. Deschamps
@es
prefLabel
Jeffrey R Deschamps
@nl
Jeffrey R Deschamps
@sl
Jeffrey R. Deschamps
@en
Jeffrey R. Deschamps
@es
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P1153
7102569818
P21
P31
P496
0000-0001-5845-0010