about
The role of innate immune responses in the outcome of interspecies competition for colonization of mucosal surfacesMechanisms of Bacterial Colonization of the Respiratory TractInhibition of the pneumococcal virulence factor StrH and molecular insights into N-glycan recognition and hydrolysisAntigenic similarities in lipopolysaccharides of Haemophilus and Neisseria and expression of a digalactoside structure also present on human cellsUnravelling the multiple functions of the architecturally intricate Streptococcus pneumoniae β-galactosidase, BgaAbeta-Defensin 1 contributes to pulmonary innate immunity in miceSynergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice.Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing.Resistance to mucosal lysozyme compensates for the fitness deficit of peptidoglycan modifications by Streptococcus pneumoniae.Mucosal lipocalin 2 has pro-inflammatory and iron-sequestering effects in response to bacterial enterobactin.The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice.Identification of the targets of cross-reactive antibodies induced by Streptococcus pneumoniae colonization.Influenza promotes pneumococcal growth during coinfection by providing host sialylated substrates as a nutrient source.Tolerance of a phage element by Streptococcus pneumoniae leads to a fitness defect during colonizationSynergistic proinflammatory responses induced by polymicrobial colonization of epithelial surfacesShielding of a lipooligosaccharide IgM epitope allows evasion of neutrophil-mediated killing of an invasive strain of nontypeable Haemophilus influenzae.Within-host competition drives selection for the capsule virulence determinant of Streptococcus pneumoniaeTLR2 signaling decreases transmission of Streptococcus pneumoniae by limiting bacterial shedding in an infant mouse Influenza A co-infection model.Pneumolysin expression by streptococcus pneumoniae protects colonized mice from influenza virus-induced diseaseCoinfection with Streptococcus pneumoniae modulates the B cell response to influenza virusModifications to the peptidoglycan backbone help bacteria to establish infectionAntibody-enhanced pneumococcal adherence requires IgA1 protease.Klebsiella pneumoniae yersiniabactin promotes respiratory tract infection through evasion of lipocalin 2Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. pneumoniae colonization in mice.Conserved mutations in the pneumococcal bacteriocin transporter gene, blpA, result in a complex population consisting of producers and cheaters.Clearance of Pneumococcal Colonization in Infants Is Delayed through Altered Macrophage Trafficking.The blp bacteriocins of Streptococcus pneumoniae mediate intraspecies competition both in vitro and in vivo.Capsule enhances pneumococcal colonization by limiting mucus-mediated clearance.Live attenuated Streptococcus pneumoniae strains induce serotype-independent mucosal and systemic protection in mice.Sensing of interleukin-1 cytokines during Streptococcus pneumoniae colonization contributes to macrophage recruitment and bacterial clearance.Identifying mutator phenotypes among fluoroquinolone-resistant strains of Streptococcus pneumoniae using fluctuation analysis.Bacterial exploitation of phosphorylcholine mimicry suppresses inflammation to promote airway infection.Protection from the acquisition of Staphylococcus aureus nasal carriage by cross-reactive antibody to a pneumococcal dehydrogenaseInteraction of lipocalin 2, transferrin, and siderophores determines the replicative niche of Klebsiella pneumoniae during pneumonia.MARCO is required for TLR2- and Nod2-mediated responses to Streptococcus pneumoniae and clearance of pneumococcal colonization in the murine nasopharynx.Peptidoglycan from the gut microbiota governs the lifespan of circulating phagocytes at homeostasis.Early bacterial colonization induces toll-like receptor-dependent transforming growth factor beta signaling in the epithelium.Natural antibody to conserved targets of Haemophilus influenzae limits colonization of the murine nasopharynx.Cross-protective mucosal immunity mediated by memory Th17 cells against Streptococcus pneumoniae lung infection.The pneumococcus: why a commensal misbehaves.
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P50
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Jeffrey N Weiser
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Jeffrey N Weiser
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Jeffrey N Weiser
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Jeffrey N Weiser
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Jeffrey N Weiser
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Jeffrey N Weiser
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Jeffrey N Weiser
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Jeffrey N Weiser
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Jeffrey N Weiser
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Jeffrey N Weiser
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P106
P21
P31
P496
0000-0001-7168-8090