Structure-activity relationship of selected meta- and para-hydroxylated non-dioxin like polychlorinated biphenyls: from single RyR1 channels to muscle dysfunction.
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Metabolism and metabolites of polychlorinated biphenylsPCB 136 atropselectively alters morphometric and functional parameters of neuronal connectivity in cultured rat hippocampal neurons via ryanodine receptor-dependent mechanismsEnantioselective transport and biotransformation of chiral hydroxylated metabolites of polychlorinated biphenyls in whole poplar plants.Variability in PCB and OH-PCB serum levels in children and their mothers in urban and rural U.S. communities.Expression and function of ryanodine receptor related pathways in PCB tolerant Atlantic killifish (Fundulus heteroclitus) from New Bedford Harbor, MA, USA.Chiral polychlorinated biphenyls: absorption, metabolism and excretion--a reviewSubacute nicotine co-exposure has no effect on 2,2',3,5',6- pentachlorobiphenyl disposition but alters hepatic cytochrome P450 expression in the male rat.Effects of thiol antioxidants on the atropselective oxidation of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) by rat liver microsomesIdentification of a novel hydroxylated metabolite of 2,2',3,5',6-pentachlorobiphenyl formed in whole poplar plants.Oxidation of polychlorinated biphenyls by liver tissue slices from phenobarbital-pretreated mice is congener-specific and atropselective.Microsomal oxidation of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) results in species-dependent chiral signatures of the hydroxylated metabolites.Editor's Highlight: Congener-Specific Disposition of Chiral Polychlorinated Biphenyls in Lactating Mice and Their Offspring: Implications for PCB Developmental Neurotoxicity.2,2',3,5',6-Pentachlorobiphenyl (PCB 95) Is Atropselectively Metabolized to para-Hydroxylated Metabolites by Human Liver Microsomes.An Extended Structure-Activity Relationship of Nondioxin-Like PCBs Evaluates and Supports Modeling Predictions and Identifies Picomolar Potency of PCB 202 Towards Ryanodine Receptors.Authentication of synthetic environmental contaminants and their (bio)transformation products in toxicology: polychlorinated biphenyls as an example.
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P2860
Structure-activity relationship of selected meta- and para-hydroxylated non-dioxin like polychlorinated biphenyls: from single RyR1 channels to muscle dysfunction.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 07 September 2013
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Structure-activity relationshi ...... hannels to muscle dysfunction.
@en
Structure-activity relationshi ...... hannels to muscle dysfunction.
@nl
type
label
Structure-activity relationshi ...... hannels to muscle dysfunction.
@en
Structure-activity relationshi ...... hannels to muscle dysfunction.
@nl
prefLabel
Structure-activity relationshi ...... hannels to muscle dysfunction.
@en
Structure-activity relationshi ...... hannels to muscle dysfunction.
@nl
P2093
P2860
P356
P1476
Structure-activity relationshi ...... hannels to muscle dysfunction.
@en
P2093
Gennady Cherednichenko
Isaac N Pessah
Sandhya M Vyas
Sudhir N Joshi
Yassaman Niknam
P2860
P304
P356
10.1093/TOXSCI/KFT202
P577
2013-09-07T00:00:00Z