Identification and functional characterization of two new transcriptional variants of the human p63 gene
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Oncogenic Intra-p53 Family Member Interactions in Human CancersdeltaNp63 has a role in maintaining epithelial integrity in airway epitheliumGenomic profiling of a human organotypic model of AEC syndrome reveals ZNF750 as an essential downstream target of mutant TP63Regulation of p63 protein stability via ubiquitin-proteasome pathway.DNA damage induces expression of WWP1 to target ΔNp63α to degradation∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites.Assessment of orthologous splicing isoforms in human and mouse orthologous genes.Transcription factor p63 regulates key genes and wound repair in human airway epithelial basal cellsΔNp63α enhances the oncogenic phenotype of osteosarcoma cells by inducing the expression of GLI2.p63 in skin development and ectodermal dysplasias.p53 Family and Cellular Stress Responses in Cancer.p53 acts as a co-repressor to regulate keratin 14 expression during epidermal cell differentiationp63 attenuates epithelial to mesenchymal potential in an experimental prostate cell model.DeltaNp63, a target of DEC1 and histone deacetylase 2, modulates the efficacy of histone deacetylase inhibitors in growth suppression and keratinocyte differentiationp63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53.p53 Family: Role of Protein Isoforms in Human Cancer.Regulation of skin aging and heart development by TAp63.A global analysis of the complex landscape of isoforms and regulatory networks of p63 in human cells and tissues.Cancer RNA-Seq Nexus: a database of phenotype-specific transcriptome profiling in cancer cellsΔNp63α Transcriptionally Regulates the Expression of CTEN That Is Associated with Prostate Cell Adhesion.Role of p63 in Development, Tumorigenesis and Cancer Progressionp63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis.Mouse p63 variants and chondrogenesis.p63α modulates c-Myc activity via direct interaction and regulation of MM1 protein stability.RNA-binding protein RBM24 regulates p63 expression via mRNA stability.The role of p63 in cancer, stem cells and cancer stem cells.Tp63 in oral development, neoplasia, and autoimmunity.A symphony of regulations centered on p63 to control development of ectoderm-derived structures.Senescence regulation by the p53 protein familyHow the TP53 family proteins TP63 and TP73 contribute to tumorigenesis: regulators and effectors.Dysregulated ΔNp63α negatively regulates the maspin promoter in keratinocytes via blocking endogenous p73 binding.From discovery to approval of an advanced therapy medicinal product-containing stem cells, in the EUFGF8, c-Abl and p300 participate in a pathway that controls stability and function of the ΔNp63α protein.ΔNp63α regulates keratinocyte proliferation by controlling PTEN expression and localization.A hidden role of the inactivated FANCD2: upregulating ΔNp63.ΔNp63 expression in four carcinoma cell lines and the effect on radioresistance--a siRNA knockdown model.Functions of TAp63 and p53 in restraining the development of metastatic cancer.EEC- and ADULT-associated TP63 mutations exhibit functional heterogeneity toward P63 responsive sequences.Pirh2 E3 ubiquitin ligase modulates keratinocyte differentiation through p63.Loss of ΔNp63α promotes mitotic exit in epithelial cells.
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Identification and functional characterization of two new transcriptional variants of the human p63 gene
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 21 August 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Identification and functional ...... variants of the human p63 gene
@en
Identification and functional ...... ariants of the human p63 gene.
@nl
type
label
Identification and functional ...... variants of the human p63 gene
@en
Identification and functional ...... ariants of the human p63 gene.
@nl
prefLabel
Identification and functional ...... variants of the human p63 gene
@en
Identification and functional ...... ariants of the human p63 gene.
@nl
P2093
P2860
P50
P356
P1476
Identification and functional ...... variants of the human p63 gene
@en
P2093
Apollonia Tullo
Elisabetta Sbisà
Marina Mangiulli
P2860
P304
P356
10.1093/NAR/GKP674
P407
P577
2009-08-21T00:00:00Z