KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification.
about
KAT2-mediated PLK4 acetylation contributes to genomic stability by preserving centrosome number.PLK4 phosphorylation of CP110 is required for efficient centriole assembly.Homozygous TAF8 mutation in a patient with intellectual disability results in undetectable TAF8 protein, but preserved RNA Polymerase II transcription.A homozygous KAT2B variant modulates the clinical phenotype of ADD3 deficiency in humans and flies.
P2860
KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 31 October 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
KAT2A/KAT2B-targeted acetylome ...... ting centrosome amplification.
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KAT2A/KAT2B-targeted acetylome ...... ting centrosome amplification.
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type
label
KAT2A/KAT2B-targeted acetylome ...... ting centrosome amplification.
@en
KAT2A/KAT2B-targeted acetylome ...... ting centrosome amplification.
@nl
prefLabel
KAT2A/KAT2B-targeted acetylome ...... ting centrosome amplification.
@en
KAT2A/KAT2B-targeted acetylome ...... ting centrosome amplification.
@nl
P2093
P2860
P50
P921
P356
P1476
KAT2A/KAT2B-targeted acetylome ...... ting centrosome amplification.
@en
P2093
Annick Dejaegere
Cédric Grauffel
Elisabeth Scheer
Jean-Marie Garnier
Mathilde Joint
Meritxell Orpinell
Pierre Gönczy
Virginie Chavant
P2860
P2888
P356
10.1038/NCOMMS13227
P407
P577
2016-10-31T00:00:00Z
P6179
1030478113