Splice site strength-dependent activity and genetic buffering by poly-G runs.
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Genetic variation of pre-mRNA alternative splicing in human populationsContext-dependent control of alternative splicing by RNA-binding proteinsEvolution of the Antisense Overlap between Genes for Thyroid Hormone Receptor and Rev-erbα and Characterization of an Exonic G-Rich Element That Regulates Splicing of TRα2 mRNACompetitive regulation of alternative splicing and alternative polyadenylation by hnRNP H and CstF64 determines acetylcholinesterase isoforms.A cytoplasmic quaking I isoform regulates the hnRNP F/H-dependent alternative splicing pathway in myelinating glia.A glycine-rich domain of hnRNP H/F promotes nucleocytoplasmic shuttling and nuclear import through an interaction with transportin 1.The splicing activator DAZAP1 integrates splicing control into MEK/Erk-regulated cell proliferation and migration.Alternative splicing of RNA triplets is often regulated and accelerates proteome evolution.Global profiling of alternative splicing events and gene expression regulated by hnRNPH/FAnalysis and design of RNA sequencing experiments for identifying isoform regulationG Run-mediated recognition of proteolipid protein and DM20 5' splice sites by U1 small nuclear RNA is regulated by context and proximity to the splice site.Impact of G-quadruplex structures and intronic polymorphisms rs17878362 and rs1642785 on basal and ionizing radiation-induced expression of alternative p53 transcriptsContext-dependent robustness to 5' splice site polymorphisms in human populations.Alternative splicing in multiple sclerosis and other autoimmune diseases.Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules.Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins.A Novel Dual Expression Platform for High Throughput Functional Screening of Phage Libraries in Product like FormatIdentification of allele-specific alternative mRNA processing via transcriptome sequencing.Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR-Cas9 library.Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma.Evolutionary dynamics of gene and isoform regulation in Mammalian tissues.The high kinetic stability of a G-quadruplex limits hnRNP F qRRM3 binding to G-tract RNA.Alternative splicing modulated by genetic variants demonstrates accelerated evolution regulated by highly conserved proteinsSRSF3 and hnRNP H1 regulate a splicing hotspot of HER2 in breast cancer cells.Splicing repression allows the gradual emergence of new Alu-exons in primate evolutionHexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxicAberrantly spliced HTT, a new player in Huntington's disease pathogenesis.Endothelial, epithelial, and fibroblast cells exhibit specific splicing programs independently of their tissue of origin.Mechanisms of toxicity in C9FTLD/ALS.Understanding splicing regulation through RNA splicing maps.InTRONs in biotech.Pick one, but be quick: 5' splice sites and the problems of too many choices.Insights into the U1 small nuclear ribonucleoprotein complex superfamily.A targeted oligonucleotide enhancer of SMN2 exon 7 splicing forms competing quadruplex and protein complexes in functional conditions.Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients.RNA G-quadruplexes: emerging mechanisms in diseaseA functional conserved intronic G run in HIV-1 intron 3 is critical to counteract APOBEC3G-mediated host restriction.Identification of functional, short-lived isoform of linker for activation of T cells (LAT).Context-dependent splicing regulation: exon definition, co-occurring motif pairs and tissue specificityFrequent gain and loss of intronic splicing regulatory elements during the evolution of vertebrates.
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Splice site strength-dependent activity and genetic buffering by poly-G runs.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 13 September 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Splice site strength-dependent activity and genetic buffering by poly-G runs.
@en
Splice site strength-dependent activity and genetic buffering by poly-G runs.
@nl
type
label
Splice site strength-dependent activity and genetic buffering by poly-G runs.
@en
Splice site strength-dependent activity and genetic buffering by poly-G runs.
@nl
prefLabel
Splice site strength-dependent activity and genetic buffering by poly-G runs.
@en
Splice site strength-dependent activity and genetic buffering by poly-G runs.
@nl
P2093
P2860
P356
P1476
Splice site strength-dependent activity and genetic buffering by poly-G runs.
@en
P2093
Christopher B Burge
Eric T Wang
Minyoung Jang
Razvan Nutiu
P2860
P2888
P304
P356
10.1038/NSMB.1661
P577
2009-09-13T00:00:00Z
P5875
P6179
1022712814