Vascular endothelial growth factor inhibition by dRK6 causes endothelial apoptosis, fibrosis, and inflammation in the heart via the Akt/eNOS axis in db/db mice.
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High glucose impairs the proliferation and increases the apoptosis of endothelial progenitor cells by suppression of Akt.Co-activation of nuclear factor-κB and myocardin/serum response factor conveys the hypertrophy signal of high insulin levels in cardiac myoblasts.Circulating endoglin concentration is not elevated in chronic kidney diseaseA protective role of ciglitazone in ox-LDL-induced rat microvascular endothelial cells via modulating PPARγ-dependent AMPK/eNOS pathwayTherapeutic effects of fenofibrate on diabetic peripheral neuropathy by improving endothelial and neural survival in db/db miceThrombospondin-1 induction in the diabetic myocardium stabilizes the cardiac matrix in addition to promoting vascular rarefaction through angiopoietin-2 upregulation.The TGF-β pathway mediates doxorubicin effects on cardiac endothelial cells.Excess maternal glucocorticoids in response to in utero undernutrition inhibit offspring angiogenesis.Inflammatory pattern recognition receptors and their ligands: factors contributing to the pathogenesis of preeclampsia.Role of Peroxisome Proliferator-Activated Receptor α in Diabetic Nephropathy.Reversibility of endothelial dysfunction in diabetes: role of polyphenols.Sex, sex steroids, and diabetic cardiomyopathy: making the case for experimental focus.Hypertension is a conditional factor for the development of cardiac hypertrophy in type 2 diabetic mice.Advanced glycation end product Nε-carboxymethyllysine induces endothelial cell injury: the involvement of SHP-1-regulated VEGFR-2 dephosphorylation.Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation.Transplantation of human umbilical cord blood cells mediated beneficial effects on apoptosis, angiogenesis and neuronal survival after hypoxic-ischemic brain injury in rats.Comparison of Non-human Primate versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction.Down-regulation of proangiogenic microRNA-126 and microRNA-132 are early modulators of diabetic cardiac microangiopathy.Long-term blockade of vascular endothelial growth factor receptor-2 aggravates the diabetic renal dysfunction associated with inactivation of the Akt/eNOS-NO axis.Oleanolic acid protects against oxidative stress‑induced human umbilical vein endothelial cell injury by activating AKT/eNOS signaling
P2860
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P2860
Vascular endothelial growth factor inhibition by dRK6 causes endothelial apoptosis, fibrosis, and inflammation in the heart via the Akt/eNOS axis in db/db mice.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 12 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Vascular endothelial growth fa ...... e Akt/eNOS axis in db/db mice.
@en
Vascular endothelial growth fa ...... e Akt/eNOS axis in db/db mice.
@nl
type
label
Vascular endothelial growth fa ...... e Akt/eNOS axis in db/db mice.
@en
Vascular endothelial growth fa ...... e Akt/eNOS axis in db/db mice.
@nl
prefLabel
Vascular endothelial growth fa ...... e Akt/eNOS axis in db/db mice.
@en
Vascular endothelial growth fa ...... e Akt/eNOS axis in db/db mice.
@nl
P2093
P2860
P356
P1433
P1476
Vascular endothelial growth fa ...... e Akt/eNOS axis in db/db mice.
@en
P2093
Cheol Whee Park
Chi-Bom Chae
Hyun Wha Chung
Hyung Wook Kim
Ji Hee Lim
Ki Dong Yoo
Sang Ju Lee
Seok Joon Shin
Sungjin Chung
Yong-Soo Kim
P2860
P304
P356
10.2337/DB09-0136
P407
P577
2009-08-12T00:00:00Z