NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies - Test2 - elhamkhani - TriplyDB

NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies

NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies

http://www.wikidata.org/entity/Q37416499

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Roles of long noncoding RNAs in chromosome domains Long non-coding RNAs as novel targets for therapy in hepatocellular carcinoma Roles of RNA-Binding Proteins in DNA Damage Response Basic biology and therapeutic implications of lncRNA The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation Long non-coding RNAs as surrogate indicators for chemical stress responses in human-induced pluripotent stem cells Involvement of Host Non-Coding RNAs in the Pathogenesis of the Influenza Virus The emerging role of long non-coding RNAs in HIV infection.The long non-coding RNA NEAT1 is responsive to neuronal activity and is associated with hyperexcitability states Functional dissection of NEAT1 using genome editing reveals substantial localization of the NEAT1_1 isoform outside paraspeckles.The RNA-binding protein SFPQ orchestrates an RNA regulon to promote axon viability Elements and machinery of non-coding RNAs: toward their taxonomy.Comparative ultrastructure of CRM1-Nucleolar bodies (CNoBs), Intranucleolar bodies (INBs) and hybrid PML/p62 bodies uncovers new facets of nuclear body dynamic and diversity The DBHS proteins SFPQ, NONO and PSPC1: a multipurpose molecular scaffold Long non-coding RNAs and control of gene expression in the immune system.The lncRNA Neat1 is required for corpus luteum formation and the establishment of pregnancy in a subpopulation of mice.Heat shock alters the expression of schizophrenia and autism candidate genes in an induced pluripotent stem cell model of the human telencephalon Non-coding RNAs and HIV: viral manipulation of host dark matter to shape the cellular environment.Protein arginine methyltransferase CARM1 attenuates the paraspeckle-mediated nuclear retention of mRNAs containing IRAlus SWI/SNF chromatin-remodeling complexes function in noncoding RNA-dependent assembly of nuclear bodies.Specific interaction with the nuclear transporter importin α2 can modulate paraspeckle protein 1 delivery to nuclear paraspeckles.Calcium-responsive transactivator (CREST) protein shares a set of structural and functional traits with other proteins associated with amyotrophic lateral sclerosis.The long noncoding RNAs NEAT1 and MALAT1 bind active chromatin sites.Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival.PSF: nuclear busy-body or nuclear facilitator?Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles.TRAP150 interacts with the RNA-binding domain of PSF and antagonizes splicing of numerous PSF-target genes in T cells Removal of unwanted variation reveals novel patterns of gene expression linked to sleep homeostasis in murine cortex Dysregulation of mitotic machinery genes precedes genome instability during spontaneous pre-malignant transformation of mouse ovarian surface epithelial cells.Development of a pipeline for automated, high-throughput analysis of paraspeckle proteins reveals specific roles for importin α proteins.Long noncoding RNAs: Re-writing dogmas of RNA processing and stability.Long noncoding RNA NEAT1 promotes laryngeal squamous cell cancer through regulating miR-107/CDK6 pathway.Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides.Enhanced expression of long non-coding RNA NEAT1 is associated with the progression of gastric adenocarcinomas.EBV noncoding RNA EBER2 interacts with host RNA-binding proteins to regulate viral gene expression.NEAT1 is Required for Survival of Breast Cancer Cells Through FUS and miR-548.Long non-coding RNA expression profile in minor salivary gland of primary Sjögren's syndrome.Chromatin remodeling complexes in the assembly of long noncoding RNA-dependent nuclear bodies.The Sam68 nuclear body is composed of two RNase-sensitive substructures joined by the adaptor HNRNPL Functional conservation of the lncRNA NEAT1 in the ancestrally diverged marsupial lineage: Evidence for NEAT1 expression and associated paraspeckle assembly during late gestation in the opossum Monodelphis domestica.

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NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies

http://www.wikidata.org/entity/Q37416499

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 30 October 2013

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

@cs

name

NEAT1 long noncoding RNA regul ...... ation within subnuclear bodies

@en

NEAT1 long noncoding RNA regul ...... tion within subnuclear bodies.

@nl

type

label

NEAT1 long noncoding RNA regul ...... ation within subnuclear bodies

@en

NEAT1 long noncoding RNA regul ...... tion within subnuclear bodies.

@nl

prefLabel

NEAT1 long noncoding RNA regul ...... ation within subnuclear bodies

@en

NEAT1 long noncoding RNA regul ...... tion within subnuclear bodies.

@nl

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MBC.E13-09-0558

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Molecular Biology of the Cell

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NEAT1 long noncoding RNA regul ...... ation within subnuclear bodies

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Akie Tanigawa

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Giorgio Virnicchi

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Gérard Pierron

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Hiroshi Kimura

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Marianne Bénard

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Ruohan Li

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Shinichi Nakagawa

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Takahide Yokoi

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Takao Naganuma

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P2860

A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains

P54nrb forms a heterodimer with PSP1 that localizes to paraspeckles in an RNA-dependent manner.

A third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single- and double-stranded RNA binding domains

ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs

The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation

Alternative 3'-end processing of long noncoding RNA initiates construction of nuclear paraspeckles

Phosphorylation-dependent regulation of PSF by GSK3 controls CD45 alternative splicing

An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles

Direct visualization of the co-transcriptional assembly of a nuclear body by noncoding RNAs

MENepsilon/beta noncoding RNAs are essential for structural integrity of nuclear paraspeckles

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169-183

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scholarly article

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10.1091/MBC.E13-09-0558

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1

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25

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2013-10-30T00:00:00Z

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24173718

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3873887

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