Hydrogen bonding between the 17beta-substituent of a neurosteroid and the GABA(A) receptor is not obligatory for channel potentiation.

Hydrogen bonding between the 17beta-substituent of a neurosteroid and the GABA(A) receptor is not obligatory for channel potentiation.

Item
http://www.wikidata.org/entity/Q37434457
Kinetic and structural determinants for GABA-A receptor potentiation by neuroactive steroids.GABAA receptor modulation by neurosteroids in models of temporal lobe epilepsies.11-trifluoromethyl-phenyldiazirinyl neurosteroid analogues: potent general anesthetics and photolabeling reagents for GABAA receptors.Occupation of either site for the neurosteroid allopregnanolone potentiates the opening of the GABAA receptor induced from either transmitter binding site.Neurosteroid analog photolabeling of a site in the third transmembrane domain of the β3 subunit of the GABA(A) receptor.Comparison of Steroid Modulation of Spontaneous Inhibitory Postsynaptic Currents in Cultured Hippocampal Neurons and Steady-State Single-Channel Currents from Heterologously Expressed α1β2γ2L GABA(A) Receptors.A novel mechanism of modulation of 5-HT₃A receptors by hydrocortisone.A neurosteroid potentiation site can be moved among GABAA receptor subunits.Development of an (S)-1-{2-[Tris(4-methoxyphenyl)methoxy]ethyl}piperidine-3-carboxylic acid [(S)-SNAP-5114] Carba Analogue Inhibitor for Murine γ-Aminobutyric Acid Transporter Type 4
P2860

Hydrogen bonding between the 17beta-substituent of a neurosteroid and the GABA(A) receptor is not obligatory for channel potentiation.

Item
http://www.wikidata.org/entity/Q37434457
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 20 August 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Hydrogen bonding between the 17beta-substituent of a neurosteroid and the GABA
@nl
Hydrogen bonding between the 1 ...... tory for channel potentiation.
@en
type
label
Hydrogen bonding between the 17beta-substituent of a neurosteroid and the GABA
@nl
Hydrogen bonding between the 1 ...... tory for channel potentiation.
@en
prefLabel
Hydrogen bonding between the 17beta-substituent of a neurosteroid and the GABA
@nl
Hydrogen bonding between the 1 ...... tory for channel potentiation.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Hydrogen bonding between the 1 ...... tory for channel potentiation.
@en
P2093
P2860
P304
P31
P356
10.1111/J.1476-5381.2009.00390.X
P407
P433
P478
P577
P5875
P698
P932