The ethanolamine branch of the Kennedy pathway is essential in the bloodstream form of Trypanosoma brucei.
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Biochemical characterization of Plasmodium falciparum CTP:phosphoethanolamine cytidylyltransferase shows that only one of the two cytidylyltransferase domains is activeBlocking variant surface glycoprotein synthesis in Trypanosoma brucei triggers a general arrest in translation initiation.Phospholipid and sphingolipid metabolism in Leishmania.Phosphatidylserine synthase 2 and phosphatidylserine decarboxylase are essential for aminophospholipid synthesis in Trypanosoma brucei.Symmetrical choline-derived dications display strong anti-kinetoplastid activity.Leishmania promastigotes lack phosphatidylserine but bind annexin V upon permeabilization or miltefosine treatment.Mitochondrial shape and function in trypanosomes requires the outer membrane protein, TbLOK1Identification of a novel lipin homologue from the parasitic protozoan Trypanosoma brucei.myo-Inositol uptake is essential for bulk inositol phospholipid but not glycosylphosphatidylinositol synthesis in Trypanosoma brucei.Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei.Plasmenylethanolamine synthesis in Leishmania major.Lipidomic analysis of bloodstream and procyclic form Trypanosoma bruceiLipid metabolism in Trypanosoma bruceiLipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexansMeclizine inhibits mitochondrial respiration through direct targeting of cytosolic phosphoethanolamine metabolism.Phosphatidylethanolamine synthesis in the parasite mitochondrion is required for efficient growth but dispensable for survival of Toxoplasma gondiiThe potential of metabolomics for Leishmania research in the post-genomics era.Intermediary metabolism in protists: a sequence-based view of facultative anaerobic metabolism in evolutionarily diverse eukaryotes.Trypanosoma brucei: a model micro-organism to study eukaryotic phospholipid biosynthesis.Exploring the metabolic state of microorganisms using metabolomics.Regulation of Phosphatidylethanolamine Homeostasis—The Critical Role of CTP:Phosphoethanolamine Cytidylyltransferase (Pcyt2).Lipid transport between the endoplasmic reticulum and mitochondria.Multiple-stage linear ion-trap with high resolution mass spectrometry towards complete structural characterization of phosphatidylethanolamines containing cyclopropane fatty acyl chain in Leishmania infantum.The Glycerol-3-Phosphate Acyltransferase TbGAT is Dispensable for Viability and the Synthesis of Glycerolipids in Trypanosoma brucei.The Trypanosoma brucei dihydroxyacetonephosphate acyltransferase TbDAT is dispensable for normal growth but important for synthesis of ether glycerophospholipids.Lipidomics and anti-trypanosomatid chemotherapy.The essential roles of cytidine diphosphate-diacylglycerol synthase in bloodstream form Trypanosoma bruceiComparative sphingolipidomics of disease-causing trypanosomatids reveal unique lifecycle- and taxonomy-specific lipid chemistries.The essential neutral sphingomyelinase is involved in the trafficking of the variant surface glycoprotein in the bloodstream form of Trypanosoma brucei.The glycosomal alkyl-dihydroxyacetonephosphate synthase TbADS is essential for the synthesis of ether glycerophospholipids in procyclic trypanosomes.Lipid analysis of Eimeria sporozoites reveals exclusive phospholipids, a phylogenetic mosaic of endogenous synthesis, and a host-independent lifestyle.
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The ethanolamine branch of the Kennedy pathway is essential in the bloodstream form of Trypanosoma brucei.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 23 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The ethanolamine branch of the ...... am form of Trypanosoma brucei.
@en
The ethanolamine branch of the ...... am form of Trypanosoma brucei.
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type
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The ethanolamine branch of the ...... am form of Trypanosoma brucei.
@en
The ethanolamine branch of the ...... am form of Trypanosoma brucei.
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prefLabel
The ethanolamine branch of the ...... am form of Trypanosoma brucei.
@en
The ethanolamine branch of the ...... am form of Trypanosoma brucei.
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The ethanolamine branch of the ...... eam form of Trypanosoma brucei
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P2093
Federica Gibellini
Terry K Smith
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P304
P356
10.1111/J.1365-2958.2009.06764.X
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P50
P577
2009-06-23T00:00:00Z