Transglutaminase-mediated intramolecular cross-linking of membrane-bound alpha-synuclein promotes amyloid formation in Lewy bodies.

Transglutaminase-mediated intramolecular cross-linking of membrane-bound alpha-synuclein promotes amyloid formation in Lewy bodies.

Item
http://www.wikidata.org/entity/Q37447970
Transglutaminase is a therapeutic target for oxidative stress, excitotoxicity and stroke: a new epigenetic kid on the CNS blockProtein transamidation by transglutaminase 2 in cells: a disputed Ca2+-dependent action of a multifunctional proteinCellular functions of tissue transglutaminasePresence of tissue transglutaminase in granular endoplasmic reticulum is characteristic of melanized neurons in Parkinson's disease brainOsteopontin undergoes polymerization in vivo and gains chemotactic activity for neutrophils mediated by integrin alpha9beta1.Tissue transglutaminase contributes to the pathogenesis of preeclampsia and stabilizes placental angiotensin receptor type 1 by ubiquitination-preventing isopeptide modification.Tissue transglutaminase-mediated glutamine deamidation of beta-amyloid peptide increases peptide solubility, whereas enzymatic cross-linking and peptide fragmentation may serve as molecular triggers for rapid peptide aggregationTransglutaminase 2 exacerbates α-synuclein toxicity in mice and yeastKeratin 8 phosphorylation regulates its transamidation and hepatocyte Mallory-Denk body formation.γ-Glutamylamines and neurodegenerative diseasesPINK1 phosphorylates transglutaminase 2 and blocks its proteasomal degradation.Inflammation, Autoimmunity, and Hypertension: The Essential Role of Tissue Transglutaminase.Vertebrate food products as a potential source of prion-like α-synuclein.
P2860

Transglutaminase-mediated intramolecular cross-linking of membrane-bound alpha-synuclein promotes amyloid formation in Lewy bodies.

Item
http://www.wikidata.org/entity/Q37447970
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 03 August 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Transglutaminase-mediated intr ...... loid formation in Lewy bodies.
@en
Transglutaminase-mediated intr ...... loid formation in Lewy bodies.
@nl
type
label
Transglutaminase-mediated intr ...... loid formation in Lewy bodies.
@en
Transglutaminase-mediated intr ...... loid formation in Lewy bodies.
@nl
prefLabel
Transglutaminase-mediated intr ...... loid formation in Lewy bodies.
@en
Transglutaminase-mediated intr ...... loid formation in Lewy bodies.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
Transglutaminase-mediated intr ...... yloid formation in Lewy bodies
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932