The Mcm complex: unwinding the mechanism of a replicative helicase.
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DNA replication at the single-molecule levelMCM-BP regulates unloading of the MCM2-7 helicase in late S phaseHow do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?The Mcm2-7 replicative helicase: a promising chemotherapeutic targetRoles of DNA helicases in the maintenance of genome integrityThe minichromosome maintenance replicative helicaseLoading and activation of DNA replicative helicases: the key step of initiation of DNA replicationStructure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocationA dominantly acting murine allele of Mcm4 causes chromosomal abnormalities and promotes tumorigenesisA Role for USP7 in DNA ReplicationStructure of the eukaryotic MCM complex at 3.8 ÅMcm2 phosphorylation and the response to replicative stressA proposal: Evolution of PCNA's role as a marker of newly replicated DNAMCM9 mutations are associated with ovarian failure, short stature, and chromosomal instabilityMCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complexInsights into the MCM functional mechanism: lessons learned from the archaeal MCM complex.Helicase loading at chromosomal origins of replicationPax6 exerts regional control of cortical progenitor proliferation via direct repression of Cdk6 and hypophosphorylation of pRbStructure and regulatory role of the C-terminal winged helix domain of the archaeal minichromosome maintenance complexThe MCM8-MCM9 complex promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination.The CMG (CDC45/RecJ, MCM, GINS) complex is a conserved component of the DNA replication system in all archaea and eukaryotes.Structural and mechanistic insights into Mcm2-7 double-hexamer assembly and functionMechanistic and biological aspects of helicase action on damaged DNA.Mutational analysis of an archaeal minichromosome maintenance protein exterior hairpin reveals critical residues for helicase activity and DNA bindingTranscriptome and proteome quantification of a tumor model provides novel insights into post-transcriptional gene regulationThe UvrD303 hyper-helicase exhibits increased processivity.Unwinding the functions of the Pif1 family helicases.A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2-7 onto DNAThe Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'.Identification of ORC1/CDC6-interacting factors in Trypanosoma brucei reveals critical features of origin recognition complex architecture.Mcm10 plays an essential role in origin DNA unwinding after loading of the CMG componentsAffinity purification of an archaeal DNA replication protein network.Chromatin replication and epigenome maintenance.A methodology for detecting the orthology signal in a PPI network at a functional complex level.Integrating gene expression and protein-protein interaction network to prioritize cancer-associated genes.Juvenile hormone-receptor complex acts on mcm4 and mcm7 to promote polyploidy and vitellogenesis in the migratory locust.Transcriptome analysis of a rotenone model of parkinsonism reveals complex I-tied and -untied toxicity mechanisms common to neurodegenerative diseases.The cellular protein MCM3AP is required for inhibition of cellular DNA synthesis by the IE86 protein of human cytomegalovirusDeregulation of the replisome factor MCMBP prompts oncogenesis in colorectal carcinomas through chromosomal instability.Transcriptome analysis of newt lens regeneration reveals distinct gradients in gene expression patterns.
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The Mcm complex: unwinding the mechanism of a replicative helicase.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The Mcm complex: unwinding the mechanism of a replicative helicase.
@en
The Mcm complex: unwinding the mechanism of a replicative helicase.
@nl
type
label
The Mcm complex: unwinding the mechanism of a replicative helicase.
@en
The Mcm complex: unwinding the mechanism of a replicative helicase.
@nl
prefLabel
The Mcm complex: unwinding the mechanism of a replicative helicase.
@en
The Mcm complex: unwinding the mechanism of a replicative helicase.
@nl
P2860
P356
P1476
The Mcm complex: unwinding the mechanism of a replicative helicase
@en
P2093
Anthony Schwacha
P2860
P304
P356
10.1128/MMBR.00019-09
P577
2009-12-01T00:00:00Z