NLRP7 affects trophoblast lineage differentiation, binds to overexpressed YY1 and alters CpG methylation.
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The specification of imprints in mammalsGenetics and Epigenetics of Recurrent Hydatidiform Moles: Basic Science and Genetic CounsellingNo evidence for mutations in NLRP7, NLRP2 or KHDC3L in women with unexplained recurrent pregnancy loss or infertilityGenes and Conditions Controlling Mammalian Pre- and Post-implantation Embryo Development.Granulosa cell-derived induced pluripotent stem cells exhibit pro-trophoblastic differentiation potential.NLRP7, Involved in Hydatidiform Molar Pregnancy (HYDM1), Interacts with the Transcriptional Repressor ZBTB16.Absence of Maternal Methylation in Biparental Hydatidiform Moles from Women with NLRP7 Maternal-Effect Mutations Reveals Widespread Placenta-Specific Imprinting.The YY1/MMP2 axis promotes trophoblast invasion at the maternal-fetal interface.The Role of Maternal-Effect Genes in Mammalian Development: Are Mammalian Embryos Really an Exception?Maternal heterozygous NLRP7 variant results in recurrent reproductive failure and imprinting disturbances in the offspring.Stem cell insights into human trophoblast lineage differentiation.The genomic architecture of NLRP7 is Alu rich and predisposes to disease-associated large deletions.NLRP7 contributes to in vitro decidualization of endometrial stromal cells.NLRP7 and KHDC3L, the two maternal-effect proteins responsible for recurrent hydatidiform moles, co-localize to the oocyte cytoskeleton.Comprehensive genotype-phenotype correlations between NLRP7 mutations and the balance between embryonic tissue differentiation and trophoblastic proliferation.A familial disorder of altered DNA-methylation
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P2860
NLRP7 affects trophoblast lineage differentiation, binds to overexpressed YY1 and alters CpG methylation.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
NLRP7 affects trophoblast line ...... Y1 and alters CpG methylation.
@en
NLRP7 affects trophoblast line ...... Y1 and alters CpG methylation.
@nl
type
label
NLRP7 affects trophoblast line ...... Y1 and alters CpG methylation.
@en
NLRP7 affects trophoblast line ...... Y1 and alters CpG methylation.
@nl
prefLabel
NLRP7 affects trophoblast line ...... Y1 and alters CpG methylation.
@en
NLRP7 affects trophoblast line ...... Y1 and alters CpG methylation.
@nl
P2093
P2860
P50
P356
P1476
NLRP7 affects trophoblast line ...... Y1 and alters CpG methylation.
@en
P2093
Bekim Sadikovic
Elisabeth M Mahen
Hsiu-Huei Peng
Ignatia B Van den Veyver
Michelina Iacovino
Sangeetha Mahadevan
Ying-Wooi Wan
P2860
P304
P356
10.1093/HMG/DDT457
P577
2013-09-18T00:00:00Z