Acid ceramidase upregulation in prostate cancer: role in tumor development and implications for therapy
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Tamoxifen regulation of sphingolipid metabolism--Therapeutic implicationsThe emergence of acid ceramidase as a therapeutic target for acute myeloid leukemia.Acid ceramidase is upregulated in AML and represents a novel therapeutic target.Discovery and evaluation of inhibitors of human ceramidase.LCL124, a cationic analog of ceramide, selectively induces pancreatic cancer cell death by accumulating in mitochondria.Clinical utility of serum autoantibodies detected by protein microarray in melanomaDisruption of sphingolipid metabolism augments ceramide-induced autophagy in preeclampsia.Protein profiling of human lung telocytes and microvascular endothelial cells using iTRAQ quantitative proteomics.Ceramide--antiestrogen nanoliposomal combinations--novel impact of hormonal therapy in hormone-insensitive breast cancer.Tamoxifen magnifies therapeutic impact of ceramide in human colorectal cancer cells independent of p53.A comparison of trabecular meshwork sphingolipids and ceramides of ocular normotensive and hypertensive states of DBA/2J miceThe endocannabinoid system in prostate cancer.The role of sphingolipids in drug metabolism and transport.Interaction of acid ceramidase inhibitor LCL521 with tumor response to photodynamic therapy and photodynamic therapy-generated vaccine.Induction of apoptosis in prostate cancer cells by the novel ceramidase inhibitor ceranib-2.Prostate cell lines as models for biomarker discovery: performance of current markers and the search for new biomarkers.Potential role of acid ceramidase in conversion of cytostatic to cytotoxic end-point in pancreatic cancer cells.Acid ceramidase is associated with an improved prognosis in both DCIS and invasive breast cancer.Potent inhibition of Acid ceramidase by novel B-13 analogues.Development of a novel FRET probe for the real-time determination of ceramidase activity.Altered Leukocyte Sphingolipid Pathway in Breast Cancer.Ceranib-2-induced suicidal erythrocyte death.Identification of the N-acylsphingosine amidohydrolase 1 gene (ASAH1) for susceptibility to schizophrenia in a Han Chinese population.Sphingosine but not sphingosine-1-phosphate stimulates suicidal erythrocyte death.
P2860
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P2860
Acid ceramidase upregulation in prostate cancer: role in tumor development and implications for therapy
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on December 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Acid ceramidase upregulation i ...... t and implications for therapy
@en
Acid ceramidase upregulation i ...... and implications for therapy.
@nl
type
label
Acid ceramidase upregulation i ...... t and implications for therapy
@en
Acid ceramidase upregulation i ...... and implications for therapy.
@nl
prefLabel
Acid ceramidase upregulation i ...... t and implications for therapy
@en
Acid ceramidase upregulation i ...... and implications for therapy.
@nl
P2093
P2860
P1476
Acid ceramidase upregulation i ...... t and implications for therapy
@en
P2093
Alicja Bielawska
James S Norris
Joseph C Cheng
Lorianne S Turner
Saeed Elojeimy
Thomas E Keane
Thomas H Beckham
P2860
P304
P356
10.1517/14728220903357512
P407
P577
2009-12-01T00:00:00Z