Rapamycin rescues vascular, metabolic and learning deficits in apolipoprotein E4 transgenic mice with pre-symptomatic Alzheimer's disease.
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Intermittent Administration of Rapamycin Extends the Life Span of Female C57BL/6J MiceThe intestinal TORC2 signaling pathway contributes to associative learning in Caenorhabditis elegans.Rapamycin: An InhibiTOR of Aging Emerges From the Soil of Easter Island.Caloric restriction preserves memory and reduces anxiety of aging mice with early enhancement of neurovascular functions.Transcriptional regulation of APP by apoE: To boldly go where no isoform has gone before: ApoE, APP transcription and AD: Hypothesised mechanisms and existing knowledge gaps.Hepatic S6K1 Partially Regulates Lifespan of Mice with Mitochondrial Complex I Deficiency.mTOR: Alzheimer's disease prevention for APOE4 carriers.Age Drives Distortion of Brain Metabolic, Vascular and Cognitive Functions, and the Gut Microbiome.Age-related impairment of metabovascular coupling during cortical spreading depolarizations.Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer's disease and vascular cognitive impairment.A Perfect sTORm: The Role of the Mammalian Target of Rapamycin (mTOR) in Cerebrovascular Dysfunction of Alzheimer's Disease: A Mini-Review.Apolipoprotein E4 mediates insulin resistance-associated cerebrovascular dysfunction and the post-prandial response.Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer's disease.Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice.APOE and Alzheimer’s Disease: Neuroimaging of Metabolic and Cerebrovascular Dysfunction.Sex Differences in Autophagy Contribute to Female Vulnerability in Alzheimer's Disease.Neuroimaging Biomarkers of mTOR Inhibition on Vascular and Metabolic Functions in Aging Brain and Alzheimer's DiseaseRepurposing Proteostasis-Modifying Drugs to Prevent or Treat Age-Related Dementia: A Systematic ReviewMolecular Mechanisms of Lithium Action: Switching the Light on Multiple Targets for Dementia Using Animal ModelsApoε4 disrupts neurovascular regulation and undermines white matter integrity and cognitive functionRapamycin Treatment Ameliorates Age-Related Accumulation of Toxic Metabolic Intermediates in Brains of the Ts65Dn Mouse Model of Down Syndrome and Aging
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Rapamycin rescues vascular, metabolic and learning deficits in apolipoprotein E4 transgenic mice with pre-symptomatic Alzheimer's disease.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 31 December 2015
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Rapamycin rescues vascular, me ...... mptomatic Alzheimer's disease.
@en
Rapamycin rescues vascular, me ...... mptomatic Alzheimer's disease.
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type
label
Rapamycin rescues vascular, me ...... mptomatic Alzheimer's disease.
@en
Rapamycin rescues vascular, me ...... mptomatic Alzheimer's disease.
@nl
prefLabel
Rapamycin rescues vascular, me ...... mptomatic Alzheimer's disease.
@en
Rapamycin rescues vascular, me ...... mptomatic Alzheimer's disease.
@nl
P2093
P2860
P356
P1476
Rapamycin rescues vascular, me ...... mptomatic Alzheimer's disease.
@en
P2093
Ai-Ling Lin
Arlan Richardson
Jordan B Jahrling
Nicholas DeRosa
Peter Romero
Veronica Galvan
Vikas Bakshi
P2860
P304
P356
10.1177/0271678X15621575
P577
2015-12-31T00:00:00Z