Flame retardant BDE-47 effectively activates nuclear receptor CAR in human primary hepatocytes.

Flame retardant BDE-47 effectively activates nuclear receptor CAR in human primary hepatocytes.

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http://www.wikidata.org/entity/Q37537458
A predictive data-driven framework for endocrine prioritization: a triazole fungicide case studyGenetic variation in the CYP2B6 gene is related to circulating 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) concentrations: an observational population-based study.RNA-Seq reveals common and unique PXR- and CAR-target gene signatures in the mouse liver transcriptome.BDE47 induces rat CYP3A1 by targeting the transcriptional regulation of miR-23b.Pyrene is a Novel Constitutive Androstane Receptor (CAR) Activator and Causes Hepatotoxicity by CAR.RNA Sequencing Reveals Age and Species Differences of Constitutive Androstane Receptor-Targeted Drug-Processing Genes in the Liver.Organophosphate flame-retardants alter adult mouse homeostasis and gene expression in a sex-dependent manner potentially through interactions with ERα.Mechanisms of Action Point Towards Combined PBDE/NDL-PCB Risk Assessment.Novel Interactions between Gut Microbiome and Host Drug-Processing Genes Modify the Hepatic Metabolism of the Environmental Chemicals Polybrominated Diphenyl Ethers.DNA Methylation Changes in Tbx3 in a Mouse Model Exposed to Polybrominated Diphenyl Ethers.Carcinogenic activity of pentabrominated diphenyl ether mixture (DE-71) in rats and mice.Persistent 6-OH-BDE-47 exposure impairs functional neuronal maturation and alters expression of neurodevelopmentally-relevant chromatin remodelers.PBDEs Altered Gut Microbiome and Bile Acid Homeostasis in Male C57BL/6 Mice
P2860

Flame retardant BDE-47 effectively activates nuclear receptor CAR in human primary hepatocytes.

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http://www.wikidata.org/entity/Q37537458
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Flame retardant BDE-47 effecti ...... in human primary hepatocytes.
@en
Flame retardant BDE-47 effecti ...... in human primary hepatocytes.
@nl
type
label
Flame retardant BDE-47 effecti ...... in human primary hepatocytes.
@en
Flame retardant BDE-47 effecti ...... in human primary hepatocytes.
@nl
prefLabel
Flame retardant BDE-47 effecti ...... in human primary hepatocytes.
@en
Flame retardant BDE-47 effecti ...... in human primary hepatocytes.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Flame retardant BDE-47 effecti ...... R in human primary hepatocytes
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P932