A missense mutation in Rev7 disrupts formation of Polζ, impairing mouse development and repair of genotoxic agent-induced DNA lesions.
about
Hypersensitivity of primordial germ cells to compromised replication-associated DNA repair involves ATM-p53-p21 signalingREV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζREV7 counteracts DNA double-strand break resection and affects PARP inhibitionDevelopment of reproductive engineering techniques at the RIKEN BioResource Center.Biallelic inactivation of REV7 is associated with Fanconi anemia.MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resectionIdentification of the first small-molecule inhibitor of the REV7 DNA repair protein interaction.
P2860
Q33880788-1F039220-8A54-4830-ACF7-086F0921D8FDQ35098093-300AA17F-A4D1-4A58-AEE1-E44075A4DC63Q36351056-0C33A23A-596F-4525-B79A-AF5ECF04C9DEQ37634684-C2321BE8-A9FF-4C77-A16D-1AD2D8940AD1Q38753157-53253430-F9B4-49A7-A2D2-5775B64F800AQ38896234-79CA08BB-849A-426A-9ED0-2F32F7F363ABQ47116816-5C796EE3-79D6-46BE-B29B-8FCB463BFE62
P2860
A missense mutation in Rev7 disrupts formation of Polζ, impairing mouse development and repair of genotoxic agent-induced DNA lesions.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 19 December 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A missense mutation in Rev7 di ...... xic agent-induced DNA lesions.
@en
A missense mutation in Rev7 di ...... xic agent-induced DNA lesions.
@nl
type
label
A missense mutation in Rev7 di ...... xic agent-induced DNA lesions.
@en
A missense mutation in Rev7 di ...... xic agent-induced DNA lesions.
@nl
prefLabel
A missense mutation in Rev7 di ...... xic agent-induced DNA lesions.
@en
A missense mutation in Rev7 di ...... xic agent-induced DNA lesions.
@nl
P2093
P2860
P356
P1476
A missense mutation in Rev7 di ...... oxic agent-induced DNA lesions
@en
P2093
Abdolrahim Abbasi
Atsuo Ogura
Heba A Degheidy
Hiroshi Yamanishi
Kouyou Akiyama
Kuniya Abe
Maryam Khalaj
Masaki Magari
Michiko Hirose
Misako Yuzuriha
P2860
P304
P356
10.1074/JBC.M113.514752
P407
P577
2013-12-19T00:00:00Z