The tinker, tailor, soldier in intracellular B12 trafficking.
about
CLYBL is a polymorphic human enzyme with malate synthase and β-methylmalate synthase activityA human vitamin B12 trafficking protein uses glutathione transferase activity for processing alkylcobalaminsNavigating the B(12) road: assimilation, delivery, and disorders of cobalaminStructures of the Human GTPase MMAA and Vitamin B 12 -dependent Methylmalonyl-CoA Mutase and Insight into Their Complex FormationStructural Basis of Multifunctionality in a Vitamin B12-processing EnzymeAutoinhibition and Signaling by the Switch II Motif in the G-protein Chaperone of a Radical B12 EnzymeCo(II)/Co(I) reduction-induced axial histidine-flipping in myoglobin reconstituted with a cobalt tetradehydrocorrin as a methionine synthase modelThe C-terminal domain of CblD interacts with CblC and influences intracellular cobalamin partitioningEthanol lowers glutathione in rat liver and brain and inhibits methionine synthase in a cobalamin-dependent mannerGenetic disorders of vitamin B12 metabolism: eight complementation groups – eight genesInborn errors of cobalamin absorption and metabolism.A G-protein editor gates coenzyme B12 loading and is corrupted in methylmalonic aciduria.Characterization of the PduS cobalamin reductase of Salmonella enterica and its role in the Pdu microcompartmentGlutathione-dependent one-electron transfer reactions catalyzed by a B₁₂ trafficking protein.Functional and structural analysis of five mutations identified in methylmalonic aciduria cblB type.Combined methylmalonic acidemia and homocystinuria, cblC type. I. Clinical presentations, diagnosis and management.Spectroscopic studies of the Salmonella enterica adenosyltransferase enzyme SeCobA: molecular-level insight into the mechanism of substrate Cob(II)alamin activation.High-resolution neutron crystallographic studies of the hydration of the coenzyme cob(II)alamin.Loss of allostery and coenzyme B12 delivery by a pathogenic mutation in adenosyltransferase.Pathogenic mutations differentially affect the catalytic activities of the human B12-processing chaperone CblC and increase futile redox cycling.Reactions of aquacobalamin and cob(II)alamin with chlorite and chlorine dioxide.Detection of Labile Low-Molecular-Mass Transition Metal Complexes in Mitochondria.Sulfur as a signaling nutrient through hydrogen sulfide.Unusual aerobic stabilization of Cob(I)alamin by a B12-trafficking protein allows chemoenzymatic synthesis of organocobalamins.Structure of Human B12 Trafficking Protein CblD Reveals Molecular Mimicry and Identifies a New Subfamily of Nitro-FMN ReductasesA vitamin B₁₂ transporter in Mycobacterium tuberculosis.Crystallographic studies on B12 binding proteins in eukaryotes and prokaryotes.Pulse radiolysis studies on the reaction of the reduced vitamin B₁₂ complex Cob(II)alamin with superoxidePharmacological chaperones as a potential therapeutic option in methylmalonic aciduria cblB type.Labile Low-Molecular-Mass Metal Complexes in Mitochondria: Trials and Tribulations of a Burgeoning FieldAccess to organometallic arylcobaltcorrins through radical synthesis: 4-ethylphenylcobalamin, a potential "antivitamin B(12)".Perturbation of neuronal cobalamin transport by lysosomal enzyme inhibitionCofactor Editing by the G-protein Metallochaperone Domain Regulates the Radical B12 Enzyme IcmF.Vitamin B12 in drug delivery: breaking through the barriers to a B12 bioconjugate pharmaceutical.High-throughput structural biology of metabolic enzymes and its impact on human diseases.Vitamin B12-derivatives-enzyme cofactors and ligands of proteins and nucleic acids.Age-related lysosomal dysfunction: an unrecognized roadblock for cobalamin trafficking?Vitamin B(12) metabolism in Mycobacterium tuberculosis.Vitamin B12 protects against superoxide-induced cell injury in human aortic endothelial cells.Cobalamin coenzyme forms are not likely to be superior to cyano- and hydroxyl-cobalamin in prevention or treatment of cobalamin deficiency.
P2860
Q24312732-AC44DD1B-3592-434C-B886-6073735C9920Q24648932-7DFAC383-99CD-40C7-B295-6656C787F2BAQ26830802-7974A6D9-6076-41B8-9739-0709EAF4E847Q27664715-16601278-E63C-4EFF-8022-2AD694C1F9BBQ27670518-2DE1FEAE-55D9-4E10-960C-E9160631C5F2Q27679846-C971C53A-1D7C-4895-9D6F-9C0239220208Q27695583-17031C15-F928-40F3-87FD-B4C3328BE84DQ28118948-3E260F36-1D1F-478C-AD62-EC28AC45DF16Q28566528-E371CD09-27E4-41AC-8A6A-0D729AC7FFE1Q29541652-EC0B56FC-360C-4110-A98C-1EFAC3749CD7Q33394088-DC7E7169-C9B3-4D52-AD40-FCA6DF8A9462Q33564491-46093A4D-1CA1-4376-B449-CBEA92E1953FQ33639840-5E5A7C08-D449-40FC-BAD4-4F9B89714408Q33718571-496A88DF-B368-454F-9F25-0047FC8B7CB7Q34101729-7627ED34-626D-4406-8B92-DE1C9DC88F69Q34448257-C1CE4FE4-56C7-425D-BE2B-70D3F9B920D0Q34782971-CC22AC53-D154-4B68-8F04-06500C942339Q35021263-16B64A3D-12E1-40C6-8EDB-21F7A120CDDAQ35058849-A47650DD-BECA-4FF2-AB38-549205AC0096Q35561002-7719545B-8ECA-48C5-AC56-A7BA451BF835Q36198412-8E05F8AA-FCE0-4F12-BED6-F6208A38D45BQ36233011-1826CCB7-F015-4444-82EF-C4C88456D2BFQ36384782-F081D0B4-BED9-4FC8-885E-A348157FE380Q36394118-8E78EB9A-2B0A-4181-8705-368E27D71D5DQ36443993-C072EAC7-7341-4677-A37E-CA33C0089EC5Q36702412-B68622BC-B28A-4FA8-A2C5-44DFA4A149F8Q36839868-80FD3E35-22E2-4782-A373-63428BF3B3A6Q37080072-BF1A8E7E-D20D-4DC1-9AEC-34060E1EA2C8Q37111958-46D4C0F7-C1BA-477A-BCE6-661CB8D7A5BAQ37309136-792DD752-CF3B-43D3-B248-F327C9A1B280Q37349393-486E7BA8-6A6C-4731-8EDA-F3CF057C1651Q37537087-D6DC53F7-44C4-4195-8650-97F8C607080DQ37705601-E372C9BC-3029-4B00-A27D-5F18393D5185Q37815507-32830B6F-5582-4358-AF66-3B4166B64DDFQ37845731-3A2C6C16-7AE5-4239-928B-6DFEB262516CQ37891827-53E70C4F-4410-4475-AB94-AD6068DD8E79Q37947954-1BFE3A9B-D48A-4320-B61B-FA045B053215Q38160534-4012E0F2-93CD-476B-BF18-6D5D13CC52A9Q38267437-6D3E255E-65AE-4BEF-8719-99F2D5DB2DF5Q38395179-B11C7020-2C7B-4B6B-AA21-24775E87998F
P2860
The tinker, tailor, soldier in intracellular B12 trafficking.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 07 August 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The tinker, tailor, soldier in intracellular B12 trafficking.
@en
The tinker, tailor, soldier in intracellular B12 trafficking.
@nl
type
label
The tinker, tailor, soldier in intracellular B12 trafficking.
@en
The tinker, tailor, soldier in intracellular B12 trafficking.
@nl
prefLabel
The tinker, tailor, soldier in intracellular B12 trafficking.
@en
The tinker, tailor, soldier in intracellular B12 trafficking.
@nl
P2093
P2860
P1476
The tinker, tailor, soldier in intracellular B12 trafficking.
@en
P2093
Carmen Gherasim
Dominique Padovani
Ruma Banerjee
P2860
P304
P356
10.1016/J.CBPA.2009.07.007
P577
2009-08-07T00:00:00Z