Crystal structure of gamma-glutamylcysteine synthetase: insights into the mechanism of catalysis by a key enzyme for glutathione homeostasis.
about
Redox-directed cancer therapeutics: molecular mechanisms and opportunitiesStructure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligaseMechanistic Details of Glutathione Biosynthesis Revealed by Crystal Structures of Saccharomyces cerevisiae Glutamate Cysteine LigaseStructural Basis for Feedback and Pharmacological Inhibition of Saccharomyces cerevisiae Glutamate Cysteine LigaseMolecular analysis of the prokaryotic ubiquitin-like protein (Pup) conjugation pathway in Mycobacterium tuberculosisNovel insight into the regulation of GSH biosynthesis in higher plants.Mechanisms of gamma-glutamylcysteine ligase regulationStructure of Mycobacterium tuberculosis glutamine synthetase in complex with a transition-state mimic provides functional insights.Actin Crosslinking Toxins of Gram-Negative BacteriaStructural basis for the redox control of plant glutamate cysteine ligase.Structural biology of plant sulfur metabolism: from assimilation to biosynthesis.Plant glutathione biosynthesis: diversity in biochemical regulation and reaction products.The Effectors and Sensory Sites of Formaldehyde-responsive Regulator FrmR and Metal-sensing VariantGenetic determination of essential residues of the Vibrio cholerae actin cross-linking domain reveals functional similarity with glutamine synthetases.Optimized CGenFF force-field parameters for acylphosphate and N-phosphonosulfonimidoyl functional groups.Recuperating Lung Decoction Attenuates the Oxidative Stress State of Chronic Obstructive Pulmonary Disease by Inhibiting the MAPK/AP-1 Signal Pathway and Regulating γ-GCS.Crystal structure of the VgrG1 actin cross-linking domain of the Vibrio cholerae type VI secretion system.Biochemical and biophysical characterization of Leishmania donovani gamma-glutamylcysteine synthetaseEpsilon-poly-L-lysine dispersity is controlled by a highly unusual nonribosomal peptide synthetase.Depupylase Dop Requires Inorganic Phosphate in the Active Site for Catalysis.The redox switch of gamma-glutamylcysteine ligase via a reversible monomer-dimer transition is a mechanism unique to plants.Probing the origins of glutathione biosynthesis through biochemical analysis of glutamate-cysteine ligase and glutathione synthetase from a model photosynthetic prokaryote.CSmetaPred: a consensus method for prediction of catalytic residues.Compounds with potential activity against Mycobacterium tuberculosis.Glutathione production by recombinant Escherichia coli expressing bifunctional glutathione synthetase.Redox-dependent stability of the γ-glutamylcysteine synthetase enzyme of Escherichia coli: a novel means of redox regulation.Molecular modeling of Trypanosoma cruzi glutamate cysteine ligase and investigation of its interactions with glutathione
P2860
Q24645584-48C90230-277D-494A-A5F5-0DAD8C96710CQ24646459-9B7F3AAB-DDF1-46E0-856C-537A4FB1B416Q27657285-7319789A-C396-4F57-A09D-3F9D15B60F9EQ27660175-DF595437-D0A9-4B24-8B9B-078EC58FB252Q28486486-4ED424E1-1BED-4F1D-BDEE-BE2C9F3C2199Q30364601-260B099A-8D03-4865-BDE3-2A04A03CC29CQ33721627-645D09BE-21B3-4DC6-85CC-47AAC945EDFBQ33906637-4BA065E8-B9BD-4522-8E1A-84884C82857CQ34011617-F961C018-CD9A-4CDF-B6DA-AA0B6E31B702Q34536831-F283C2D2-3D5D-4A41-A14C-0CBF37FB5199Q34638385-65FD2B3E-2106-4564-B684-2CF2FA95141FQ35970884-841B42A6-5BEE-49BD-8BAA-1DA964F7E2A3Q37243251-8564AAD9-134D-47EB-826C-6AC50662324EQ37354793-622F8DA6-64C4-4003-AFB2-6080E29FDDADQ37524043-5DED3398-38CA-4281-A962-569EE016EF00Q37734369-C0C82ECA-3162-4507-A157-CD79943D2DCAQ39296341-DA3D3B30-AA4B-4778-A1DB-872363A417EDQ41682691-8320076F-402E-4629-86C9-F33EBE72E526Q42602789-89D0392D-5D2F-43D1-999B-2D00064A3318Q46428175-5F44BDA3-8088-48C4-BE17-955378D34815Q46697262-DFED5D45-437A-461C-88E0-783E1986EA80Q46961656-1A8ED2EF-9BDB-42E3-A5E8-13FC6EA02CB4Q47121849-756F3C6D-F09D-43A6-A390-EB68F0A5B41EQ50044336-C8BD0D4B-55E0-4B30-99AC-491C63FC9B82Q51637435-6F439EDF-ACED-464D-BF6F-656B1ADE4B52Q54324287-1C425FE2-88A6-4944-B712-4A722C8EABF5Q57833404-EAD1BF32-F281-4346-ACCD-FD0F9467F1AE
P2860
Crystal structure of gamma-glutamylcysteine synthetase: insights into the mechanism of catalysis by a key enzyme for glutathione homeostasis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 11 October 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Crystal structure of gamma-glu ...... e for glutathione homeostasis.
@en
Crystal structure of gamma-glu ...... e for glutathione homeostasis.
@nl
type
label
Crystal structure of gamma-glu ...... e for glutathione homeostasis.
@en
Crystal structure of gamma-glu ...... e for glutathione homeostasis.
@nl
prefLabel
Crystal structure of gamma-glu ...... e for glutathione homeostasis.
@en
Crystal structure of gamma-glu ...... e for glutathione homeostasis.
@nl
P2093
P2860
P356
P1476
Crystal structure of gamma-glu ...... me for glutathione homeostasis
@en
P2093
Akira Kimura
Hiroshi Nii
Jun Hiratake
Jun'ichi Oda
Toru Nakatsu
P2860
P304
15052-15057
P356
10.1073/PNAS.0403277101
P407
P577
2004-10-11T00:00:00Z