CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation.
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Microtubule-Binding Proteins as Promising Biomarkers of Paclitaxel Sensitivity in Cancer ChemotherapyThe deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cellsNew frontiers: discovering cilia-independent functions of cilia proteinsRegulation of spindle integrity and mitotic fidelity by BCCIPMicrotubule-associated protein Mdp3 promotes breast cancer growth and metastasisCYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6.HDAC6 deacetylase activity is critical for lipopolysaccharide-induced activation of macrophagesCYLD Regulates Noscapine Activity in Acute Lymphoblastic Leukemia via a Microtubule-Dependent Mechanism.CYLD-mediated signaling and diseases.Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerizationRegulation of NDR1 activity by PLK1 ensures proper spindle orientation in mitosisDeacetylation of α-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly.Identification of novel microtubule-binding proteins by taxol-mediated microtubule stabilization and mass spectrometry analysis.Cell Fate Decision Making through Oriented Cell Division.Cep70 overexpression stimulates pancreatic cancer by inducing centrosome abnormality and microtubule disorganization.Reciprocal activation between STAT3 and miR-181b regulates the proliferation of esophageal cancer stem-like cells via the CYLD pathway.Proto-Oncogenic Src Phosphorylates EB1 to Regulate the Microtubule-Focal Adhesion Crosstalk and Stimulate Cell Migration.ASK1 controls spindle orientation and positioning by phosphorylating EB1 and stabilizing astral microtubules.Functional interplay between cylindromatosis and histone deacetylase 6 in ciliary homeostasis revealed by phenotypic analysis of double knockout mice.Apoptosis signal-regulating kinase 1 exhibits oncogenic activity in pancreatic cancer.Phosphorylation of EB1 regulates the recruitment of CLIP-170 and p150glued to the plus ends of astral microtubulesApoptosis-linked gene 2 promotes breast cancer growth and metastasis by regulating the cytoskeleton.Ubiquitin in regulation of spindle apparatus and its positioning: implications in development and disease.Characterization of a novel EB1 acetylation site important for the regulation of microtubule dynamics and cargo recruitment.Epithelial spindle orientation diversities and uncertainties: recent developments and lingering questions.Mechanisms of regulation and diversification of deubiquitylating enzyme function.Cylindromatosis--A Protective Molecule against Liver Diseases.Activated proline-rich tyrosine kinase 2 regulates meiotic spindle assembly in the mouse oocyte.ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules.Regulation of mitotic spindle orientation during epidermal stratification.Deregulated ALG-2/HEBP2 axis alters microtubule dynamics and mitotic spindle behavior to stimulate cancer development.Dynamic ubiquitin signaling in cell cycle regulation.Regulation of paclitaxel activity by microtubule-associated proteins in cancer chemotherapy.The connections of Wnt pathway components with cell cycle and centrosome: side effects or a hidden logic?The B-box module of CYLD is responsible for its intermolecular interaction and cytoplasmic localization.MALT1 Protease Activation Triggers Acute Disruption of Endothelial Barrier Integrity via CYLD Cleavage.Palladin is a novel microtubule-associated protein responsible for spindle orientation.Regulation of the cell cycle and centrosome biology by deubiquitylases.Effects of FSTL1 on the proliferation and motility of breast cancer cells and vascular endothelial cells.EB1 phosphorylation mediates the functions of ASK1 in pancreatic cancer development.
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CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 27 January 2014
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
CYLD regulates spindle orienta ...... in/dynactin complex formation.
@en
CYLD regulates spindle orienta ...... in/dynactin complex formation.
@nl
type
label
CYLD regulates spindle orienta ...... in/dynactin complex formation.
@en
CYLD regulates spindle orienta ...... in/dynactin complex formation.
@nl
prefLabel
CYLD regulates spindle orienta ...... in/dynactin complex formation.
@en
CYLD regulates spindle orienta ...... in/dynactin complex formation.
@nl
P2093
P2860
P50
P356
P1476
CYLD regulates spindle orienta ...... in/dynactin complex formation.
@en
P2093
P2860
P304
P356
10.1073/PNAS.1319341111
P407
P577
2014-01-27T00:00:00Z