NUMB inhibition of NOTCH signalling as a therapeutic target in prostate cancer. - Test2 - elhamkhani - TriplyDB

NUMB inhibition of NOTCH signalling as a therapeutic target in prostate cancer.

NUMB inhibition of NOTCH signalling as a therapeutic target in prostate cancer.

http://www.wikidata.org/entity/Q37589507

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Regulating Axonal Responses to Injury: The Intersection between Signaling Pathways Involved in Axon Myelination and The Inhibition of Axon Regeneration The role of GATA2 in lethal prostate cancer aggressiveness.Hepatitis B Virus HBx Activates Notch Signaling via Delta-Like 4/Notch1 in Hepatocellular Carcinoma.A Novel Role of Numb as A Regulator of Pro-inflammatory Cytokine Production in Macrophages in Response to Toll-like Receptor 4 The pineal gland: A model for adrenergic modulation of ubiquitin ligases Hypoxia regulates Notch-3 mRNA and receptor activation in prostate cancer cells.NUMB negatively regulates the epithelial-mesenchymal transition of triple-negative breast cancer by antagonizing Notch signaling.Notch signaling in the prostate: critical roles during development and in the hallmarks of prostate cancer biology.Epithelial-to-Mesenchymal Plasticity Harnesses Endocytic Circuitries.Overexpression of CXCL3 can enhance the oncogenic potential of prostate cancer.Notch2 signaling contributes to cell growth, invasion, and migration in salivary adenoid cystic carcinoma.Role of Notch signaling during lipopolysaccharide-induced preterm labor.Up-regulation of microRNA let-7c by quercetin inhibits pancreatic cancer progression by activation of Numbl.MiR-129 blocks estrogen induction of NOTCH signaling activity in breast cancer stem-like cells.Numb prevents a complete epithelial-mesenchymal transition by modulating Notch signalling.Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Cells.Notch signaling and progenitor/ductular reaction in steatohepatitis.Cancer stem cells as targets for immunotherapy.HERV Envelope Proteins: Physiological Role and Pathogenic Potential in Cancer and Autoimmunity.Activation of Notch pathway is linked with epithelial-mesenchymal transition in prostate cancer cells.NUMB and NUMBL differences in gene regulation.Dr. Jekyll and Mr. Hyde: MAP17's up-regulation, a crosspoint in cancer and inflammatory diseases.Serum levels of miR-320 family members are associated with clinical parameters and diagnosis in prostate cancer patients.Changes of signal transductivity and robustness of gene regulatory network in the carcinogenesis of leukemic subtypes via microarray sample data.

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NUMB inhibition of NOTCH signalling as a therapeutic target in prostate cancer.

http://www.wikidata.org/entity/Q37589507

description

article científic

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article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 19 August 2014

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

NUMB inhibition of NOTCH signalling as a therapeutic target in prostate cancer.

@en

NUMB inhibition of NOTCH signalling as a therapeutic target in prostate cancer.

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type

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NUMB inhibition of NOTCH signalling as a therapeutic target in prostate cancer.

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NUMB inhibition of NOTCH signalling as a therapeutic target in prostate cancer.

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prefLabel

NUMB inhibition of NOTCH signalling as a therapeutic target in prostate cancer.

@en

NUMB inhibition of NOTCH signalling as a therapeutic target in prostate cancer.

@nl

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NRUROL.2014.195

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Nature Reviews Urology

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NUMB inhibition of NOTCH signalling as a therapeutic target in prostate cancer.

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Angela N Flores

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Armelle Meunier

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Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase

Soluble Jagged 1 represses the function of its transmembrane form to induce the formation of the Src-dependent chord-like phenotype

Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal

Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma

Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor

Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module

Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover

Human deltex is a conserved regulator of Notch signalling

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways

LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation

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nrurol.2014.195

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499-507

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scholarly article

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10.1038/NRUROL.2014.195

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2014-08-19T00:00:00Z

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25134838

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