Determination of Cellular Processing Rates for a Trastuzumab-Maytansinoid Antibody-Drug Conjugate (ADC) Highlights Key Parameters for ADC Design.
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Evolution of Antibody-Drug Conjugate Tumor Disposition Model to Predict Preclinical Tumor Pharmacokinetics of Trastuzumab-Emtansine (T-DM1).Antigen-responsive molecular sensor enables real-time tumor-specific imaging.Measurement and Mathematical Characterization of Cell-Level Pharmacokinetics of Antibody-Drug Conjugates: A Case Study with Trastuzumab-vc-MMAE.Development of a Translational Physiologically Based Pharmacokinetic Model for Antibody-Drug Conjugates: a Case Study with T-DM1.Quantitative characterization of in vitro bystander effect of antibody-drug conjugates.Intracellular trafficking of new anticancer therapeutics: antibody-drug conjugates.Transport of drugs from blood vessels to tumour tissue.Chemically triggered drug release from an antibody-drug conjugate leads to potent antitumour activity in mice.
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Determination of Cellular Processing Rates for a Trastuzumab-Maytansinoid Antibody-Drug Conjugate (ADC) Highlights Key Parameters for ADC Design.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 February 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Determination of Cellular Proc ...... Key Parameters for ADC Design.
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Determination of Cellular Proc ...... sinoid Antibody-Drug Conjugate
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type
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Determination of Cellular Proc ...... Key Parameters for ADC Design.
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Determination of Cellular Proc ...... sinoid Antibody-Drug Conjugate
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Determination of Cellular Proc ...... Key Parameters for ADC Design.
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Determination of Cellular Proc ...... sinoid Antibody-Drug Conjugate
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Determination of Cellular Proc ...... Key Parameters for ADC Design
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Alison M Betts
Chethana Kulkarni
K Dane Wittrup
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10.1208/S12248-016-9892-3
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2016-02-24T00:00:00Z
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1013891445