The Rho-GEF Kalirin regulates bone mass and the function of osteoblasts and osteoclasts. - Test2 - elhamkhani - TriplyDB

The Rho-GEF Kalirin regulates bone mass and the function of osteoblasts and osteoclasts.

The Rho-GEF Kalirin regulates bone mass and the function of osteoblasts and osteoclasts.

http://www.wikidata.org/entity/Q37602925

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An N-terminal Amphipathic Helix Binds Phosphoinositides and Enhances Kalirin Sec14 Domain-mediated Membrane Interactions.Effect of serum from postmenopausal women with osteoporosis exhibiting the Kidney-Yang deficiency pattern on bone formation in an hFOB 1.19 human osteoblastic cell line.Exome sequencing discloses KALRN homozygous variant as likely cause of intellectual disability and short stature in a consanguineous pedigree Exposure to Excess Phenobarbital Negatively Influences the Osteogenesis of Chick Embryos Inhibition of microtubule dynamics affects podosome belt formation during osteoclast induction.Characterization of complex, co-adapted skeletal biomechanics phenotypes: a needed paradigm shift in the genetics of bone structure and function.Alternate promoter usage generates two subpopulations of the neuronal RhoGEF Kalirin-7.Brain Region and Isoform-Specific Phosphorylation Alters Kalirin SH2 Domain Interaction Sites and Calpain Sensitivity.The RhoGAP Myo9b Promotes Bone Growth by Mediating Osteoblastic Responsiveness to IGF-1.MMP14 is a novel target of PTH signaling in osteocytes that controls resorption by regulating soluble RANKL production.

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The Rho-GEF Kalirin regulates bone mass and the function of osteoblasts and osteoclasts.

http://www.wikidata.org/entity/Q37602925

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

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scientific article published on 28 December 2013

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

The Rho-GEF Kalirin regulates bone mass and the function of osteoblasts and osteoclasts.

@en

The Rho-GEF Kalirin regulates bone mass and the function of osteoblasts and osteoclasts.

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type

label

The Rho-GEF Kalirin regulates bone mass and the function of osteoblasts and osteoclasts.

@en

The Rho-GEF Kalirin regulates bone mass and the function of osteoblasts and osteoclasts.

@nl

prefLabel

The Rho-GEF Kalirin regulates bone mass and the function of osteoblasts and osteoclasts.

@en

The Rho-GEF Kalirin regulates bone mass and the function of osteoblasts and osteoclasts.

@nl

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J.BONE.2013.12.023

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The Rho-GEF Kalirin regulates bone mass and the function of osteoblasts and osteoclasts.

@en

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Betty A Eipper

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Kornchanok Wayakanon

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Matthew R Allen

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Pierre P Eleniste

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Prashant Mandela

http://www.w3.org/2001/XMLSchema#string

Richard E Mains

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Su Huang

http://www.w3.org/2001/XMLSchema#string

P2860

Kalirin-7 is required for synaptic structure and function

Kalirin-7 controls activity-dependent structural and functional plasticity of dendritic spines

GEFs and GAPs: critical elements in the control of small G proteins

Kalrn plays key roles within and outside of the nervous system

Kalirin, a multifunctional Rho guanine nucleotide exchange factor, is necessary for maintenance of hippocampal pyramidal neuron dendrites and dendritic spines

Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells.

Estrogen action and cytoplasmic signaling cascades. Part I: membrane-associated signaling complexes.

Genomic organization and differential expression of Kalirin isoforms.

Estrogen action and cytoplasmic signaling pathways. Part II: the role of growth factors and phosphorylation in estrogen signaling.

Osteocyte network; a negative regulatory system for bone mass augmented by the induction of Rankl in osteoblasts and Sost in osteocytes at unloading.

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235-245

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scholarly article

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10.1016/J.BONE.2013.12.023

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60

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Angela Bruzzaniti

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2013-12-28T00:00:00Z

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24380811

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