Complex and context dependent regulation of hematopoiesis by TGF-beta superfamily signaling.
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Cutting the brakes on hematopoietic regeneration by blocking TGFβ to limit chemotherapy-induced myelosuppressionThe Role of Myeloid-Derived Suppressor Cells (MDSC) in Cancer ProgressionBMP-mediated specification of the erythroid lineage suppresses endothelial development in blood island precursorsLung as a Niche for Hematopoietic Progenitors.Specific control of BMP signaling and mesenchymal differentiation by cytoplasmic phosphatase PPM1H.The aryl hydrocarbon receptor: regulation of hematopoiesis and involvement in the progression of blood diseases.Divergent molecular mechanisms underlying the pleiotropic functions of macrophage inhibitory cytokine-1 in cancerZnf45l affects primitive hematopoiesis by regulating transforming growth factor-β signalingA phase 1 study of ACE-536, a regulator of erythroid differentiation, in healthy volunteers.Lysophosphatidic acid acts as a nutrient-derived developmental cue to regulate early hematopoiesis.Niche heterogeneity in the bone marrowGeneration of mice carrying a knockout-first and conditional-ready allele of transforming growth factor beta2 geneTranscriptional regulation of the human P450 oxidoreductase gene: hormonal regulation and influence of promoter polymorphisms.MiR-24 is required for hematopoietic differentiation of mouse embryonic stem cells.Smad1 signaling restricts hematopoietic potential after promoting hemangioblast commitment.TGF-β signaling and its role in the regulation of hematopoietic stem cells.The kinase activity of the Ser/Thr kinase BUB1 promotes TGF-β signaling.An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia.Loss of Folliculin Disrupts Hematopoietic Stem Cell Quiescence and Homeostasis Resulting in Bone Marrow Failure.Normal ABL1 is a tumor suppressor and therapeutic target in human and mouse leukemias expressing oncogenic ABL1 kinases.Inhibiting TGFβ1 has a protective effect on mouse bone marrow suppression following ionizing radiation exposure in vitroEndothelial Smad4 restrains the transition to hematopoietic progenitors via suppression of ERK activation.IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigeneticsThe role of Smad signaling in vascular and hematopoietic development revealed by studies using genetic mouse models.Activin receptor antagonists for cancer-related anemia and bone disease.Tumor microenvironment and myeloid-derived suppressor cells.Dormancy in solid tumors: implications for prostate cancer.The role of the bone morphogenetic proteins in leukaemic stem cell persistence.Immune-mediated pathology in Duchenne muscular dystrophy.The SKI proto-oncogene enhances the in vivo repopulation of hematopoietic stem cells and causes myeloproliferative disease.Divisional history and hematopoietic stem cell function during homeostasis.Emerging biological therapies for the treatment of myelodysplastic syndromes.Regulation of Hematopoiesis and Hematological Disease by TGF-β Family Signaling Molecules.Deconstructing the Complexity of TGFβ Signaling in Hematopoietic Stem Cells: Quiescence and Beyond.The small peptide OGP(10-14) reduces proliferation and induces differentiation of TPO-primed M07-e cells through RhoA/TGFbeta1/SFK pathway.Transcriptional profiling of polycythemia vera identifies gene expression patterns both dependent and independent from the action of JAK2V617F.Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine β-thalassemia.Myeloid-derived suppressor cells interact with tumors in terms of myelopoiesis, tumorigenesis and immunosuppression: thick as thieves.Bmp signalling in filiform tongue papillae development.p190-B RhoGAP and intracellular cytokine signals balance hematopoietic stem and progenitor cell self-renewal and differentiation.
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P2860
Complex and context dependent regulation of hematopoiesis by TGF-beta superfamily signaling.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Complex and context dependent ...... GF-beta superfamily signaling.
@en
Complex and context dependent ...... GF-beta superfamily signaling.
@nl
type
label
Complex and context dependent ...... GF-beta superfamily signaling.
@en
Complex and context dependent ...... GF-beta superfamily signaling.
@nl
prefLabel
Complex and context dependent ...... GF-beta superfamily signaling.
@en
Complex and context dependent ...... GF-beta superfamily signaling.
@nl
P2093
P1476
Complex and context dependent ...... GF-beta superfamily signaling.
@en
P2093
Göran Karlsson
Sofie Singbrant Söderberg
Stefan Karlsson
P2860
P356
10.1111/J.1749-6632.2009.04569.X
P407
P577
2009-09-01T00:00:00Z