Latent TGFbeta1 overexpression in keratinocytes results in a severe psoriasis-like skin disorder. - Test2 - elhamkhani - TriplyDB

Latent TGFbeta1 overexpression in keratinocytes results in a severe psoriasis-like skin disorder.

Latent TGFbeta1 overexpression in keratinocytes results in a severe psoriasis-like skin disorder.

http://www.wikidata.org/entity/Q37617085

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Gene from a psoriasis susceptibility locus primes the skin for inflammation Connexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response.Activin controls skin morphogenesis and wound repair predominantly via stromal cells and in a concentration-dependent manner via keratinocytes Putting together the psoriasis puzzle: an update on developing targeted therapies Regulation of the psoriatic chemokine CCL20 by E3 ligases Trim32 and Piasy in keratinocytes Psoriasiform dermatitis is driven by IL-36-mediated DC-keratinocyte crosstalk TGF-β sensitivity is determined by N-linked glycosylation of the type II TGF-β receptor Drosophila spichthyin inhibits BMP signaling and regulates synaptic growth and axonal microtubules.Epidermal Smad4 deletion results in aberrant wound healing.Persistent inflammation and angiogenesis during wound healing in K14-directed Hoxb13 transgenic mice.A global gene expression analysis of the peripheral blood mononuclear cells reveals the gene expression signature in psoriasis.Distinct mechanisms of TGF-beta1-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis.Genome-wide expression profiling of five mouse models identifies similarities and differences with human psoriasis.Inflammatory skin disease in K5.hTGF-beta1 transgenic mice is not dependent on the IL-23/Th17 inflammatory pathway.Halting angiogenesis by non-viral somatic gene therapy alleviates psoriasis and murine psoriasiform skin lesions.ID family protein expression and regulation in hypoxic pulmonary hypertension.Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins.Involvement of IL-9 in Th17-associated inflammation and angiogenesis of psoriasis Epidermal barrier formation and recovery in skin disorders.Depletion of antigen-presenting cells by clodronate liposomes reverses the psoriatic skin phenotype in KC-Tie2 mice.Loss of transforming growth factor-beta type II receptor promotes metastatic head-and-neck squamous cell carcinoma.Platelet-activating factor blockade inhibits the T-helper type 17 cell pathway and suppresses psoriasis-like skin disease in K5.hTGF-β1 transgenic mice.Suppression of molecular inflammatory pathways by Toll-like receptor 7, 8, and 9 antagonists in a model of IL-23-induced skin inflammation.The role of Smad7 in oral mucositis.Temporal smad7 transgene induction in mouse epidermis accelerates skin wound healing The pro-inflammatory role of TGFβ1: a paradox?TGF-beta induces p65 acetylation to enhance bacteria-induced NF-kappaB activation.Cross Talk between Proliferative, Angiogenic, and Cellular Mechanisms Orchestred by HIF-1α in Psoriasis.Genetically modified mice as a tool to study inflammatory skin diseases.MicroRNA-132 enhances transition from inflammation to proliferation during wound healing.TGFβ1 overexpression by keratinocytes alters skin dendritic cell homeostasis and enhances contact hypersensitivity Ligand-dependent actions of the vitamin D receptor are required for activation of TGF-β signaling during the inflammatory response to cutaneous injury The Role of TGFβ Signaling in Squamous Cell Cancer: Lessons from Mouse Models In vivo pharmacological disease models for psoriasis and atopic dermatitis in drug discovery.Animal models of skin disease for drug discovery.Down-regulation of miRNAs during delayed wound healing in diabetes: Role of Dicer.Mice overexpressing latent TGF-beta1 are protected against renal fibrosis in obstructive kidney disease Bi-compartmental communication contributes to the opposite proliferative behavior of Notch1-deficient hair follicle and epidermal keratinocytes.Pathophysiology of psoriasis: recent advances on IL-23 and Th17 cytokines.Antimicrobial Peptide LL37 and MAVS Signaling Drive Interferon-β Production by Epidermal Keratinocytes during Skin Injury.

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Latent TGFbeta1 overexpression in keratinocytes results in a severe psoriasis-like skin disorder.

http://www.wikidata.org/entity/Q37617085

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on April 2004

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Latent TGFbeta1 overexpression ...... psoriasis-like skin disorder.

@en

Latent TGFbeta1 overexpression ...... psoriasis-like skin disorder.

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type

label

Latent TGFbeta1 overexpression ...... psoriasis-like skin disorder.

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Latent TGFbeta1 overexpression ...... psoriasis-like skin disorder.

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prefLabel

Latent TGFbeta1 overexpression ...... psoriasis-like skin disorder.

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Latent TGFbeta1 overexpression ...... psoriasis-like skin disorder.

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SJ.EMBOJ.7600183

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The EMBO Journal

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Latent TGFbeta1 overexpression ...... psoriasis-like skin disorder.

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Allen G Li

http://www.w3.org/2001/XMLSchema#string

Donna Wang

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Xiao-Jing Wang

http://www.w3.org/2001/XMLSchema#string

Xin-Hua Feng

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P2860

Controlling the angiogenic switch: a balance between two distinct TGF-b receptor signaling pathways

Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling

Activin receptor-like kinase 1 is implicated in the maturation phase of angiogenesis

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

Sequences 5' of the bovine keratin 5 gene direct tissue- and cell-type-specific expression of a lacZ gene in the adult and during development

Wound healing in MIP-1alpha(-/-) and MCP-1(-/-) mice

Healing of burn wounds in transgenic mice overexpressing transforming growth factor-beta 1 in the epidermis

NF-kappaB: a key role in inflammatory diseases

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1770-1781

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scholarly article

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10.1038/SJ.EMBOJ.7600183

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2004-04-01T00:00:00Z

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15057277

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