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Interactions of metals and Apolipoprotein E in Alzheimer's diseaseA synthetic peptide with the putative iron binding motif of amyloid precursor protein (APP) does not catalytically oxidize ironCurcumin and its derivatives: their application in neuropharmacology and neuroscience in the 21st centuryOxidative stress in Alzheimer's and Parkinson's diseases: insights from the yeast Saccharomyces cerevisiaeMolecular basis of neurodegeneration and neurodevelopmental defects in Menkes diseaseDeficiency of the copper chaperone for superoxide dismutase increases amyloid-β productionLink between Aluminum and the Pathogenesis of Alzheimer's Disease: The Integration of the Aluminum and Amyloid Cascade HypothesesDietary cholesterol degrades rabbit long term memory for discrimination learning but facilitates acquisition of discrimination reversalA new thiophenyl pyrazoline fluorescent probe for Cu2+ in aqueous solution and imaging in live cell.Isoxazolotacrines as non-toxic and selective butyrylcholinesterase inhibitors for Alzheimer's disease.Elevated copper in the amyloid plaques and iron in the cortex are observed in mouse models of Alzheimer's disease that exhibit neurodegenerationMetal imaging in neurodegenerative diseases.Role of glutaredoxin1 and glutathione in regulating the activity of the copper-transporting P-type ATPases, ATP7A and ATP7B.Cholesterol increases ventricular volume in a rabbit model of Alzheimer's disease.Novel transporter required for biogenesis of cbb3-type cytochrome c oxidase in Rhodobacter capsulatusCopper and iron in Alzheimer's disease: a systematic review and its dietary implications.Cu(2+) affects amyloid-β (1-42) aggregation by increasing peptide-peptide binding forces.Presenilins promote the cellular uptake of copper and zinc and maintain copper chaperone of SOD1-dependent copper/zinc superoxide dismutase activity.Neuroprotective strategies involving ROS in Alzheimer disease.Cu K-edge X-ray absorption spectroscopy reveals differential copper coordination within amyloid-β oligomers compared to amyloid-β monomers.Fluorescence lifetime imaging of physiological free Cu(II) levels in live cells with a Cu(II)-selective carbonic anhydrase-based biosensor.Gender effects on plasma and brain copper.Copper Inhibits NMDA Receptor-Independent LTP and Modulates the Paired-Pulse Ratio after LTP in Mouse Hippocampal SlicesAβ neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-D-aspartate receptorsThe human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging: implications for cognitive health.Environmental risk factors for dementia: a systematic review.Alzheimer's disease-associated neurotoxic peptide amyloid-β impairs base excision repair in human neuroblastoma cellsOpportunities in multidimensional trace metal imaging: taking copper-associated disease research to the next levelNanoprobing of the effect of Cu(2+) cations on misfolding, interaction and aggregation of amyloid β peptide.Natural compounds may open new routes to treatment of amyloid diseasesMetalloproteomics: principles, challenges and applications to neurodegeneration.Natural products as a source of Alzheimer's drug leads.Local structure and global patterning of Cu2+ binding in fibrillar amyloid-β [Aβ(1-40)] proteinRole of the P-Type ATPases, ATP7A and ATP7B in brain copper homeostasis.Copper and protons directly activate the zinc-activated channelCapturing a reactive state of amyloid aggregates: NMR-based characterization of copper-bound Alzheimer disease amyloid β-fibrils in a redox cycle.Novel drug targets based on metallobiology of Alzheimer's disease.Interactions of Zn(II) and Cu(II) ions with Alzheimer's amyloid-beta peptide. Metal ion binding, contribution to fibrillization and toxicity.Metal ions, Alzheimer's disease and chelation therapy.The biological occurrence and trafficking of cobalt.
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 28 October 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Copper in the brain and Alzheimer's disease.
@en
Copper in the brain and Alzheimer's disease.
@nl
type
label
Copper in the brain and Alzheimer's disease.
@en
Copper in the brain and Alzheimer's disease.
@nl
prefLabel
Copper in the brain and Alzheimer's disease.
@en
Copper in the brain and Alzheimer's disease.
@nl
P2860
P1476
Copper in the brain and Alzheimer's disease.
@en
P2093
Robert Alan Cherny
P2860
P2888
P356
10.1007/S00775-009-0600-Y
P577
2009-10-28T00:00:00Z