Combinatorial H3K9acS10ph histone modification in IgH locus S regions targets 14-3-3 adaptors and AID to specify antibody class-switch DNA recombination.
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Epigenetics of Peripheral B-Cell Differentiation and the Antibody ResponseEpigenetic Codes Programing Class Switch RecombinationRegulation of Aicda expression and AID activityRNA Exosome Regulates AID DNA Mutator Activity in the B Cell GenomeAID targeting: old mysteries and new challengesEμ and 3'RR IgH enhancers show hierarchic unilateral dependence in mature B-cells.MicroRNAs in lupus.Histone deacetylase inhibitors upregulate B cell microRNAs that silence AID and Blimp-1 expression for epigenetic modulation of antibody and autoantibody responses.Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination.Induction of activation-induced cytidine deaminase-targeting adaptor 14-3-3γ is mediated by NF-κB-dependent recruitment of CFP1 to the 5'-CpG-3'-rich 14-3-3γ promoter and is sustained by E2A.Rad52 competes with Ku70/Ku86 for binding to S-region DSB ends to modulate antibody class-switch DNA recombination.AIDing Chromatin and Transcription-Coupled Orchestration of Immunoglobulin Class-Switch Recombination.Small Molecule Inhibition of Rab7 Impairs B Cell Class Switching and Plasma Cell Survival To Dampen the Autoantibody Response in Murine Lupus.Nascent Connections: R-Loops and Chromatin Patterning.Kin17 facilitates multiple double-strand break repair pathways that govern B cell class switching.A Neuronal Activity-Dependent Dual Function Chromatin-Modifying Complex Regulates Arc Expression(1,2,3).Editorial: Epigenetics of B Cells and Antibody Responses.B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses.B cell TLR1/2, TLR4, TLR7 and TLR9 interact in induction of class switch DNA recombination: modulation by BCR and CD40, and relevance to T-independent antibody responses.Identification of multiple roles for histone acetyltransferase 1 in replication-coupled chromatin assembly.Epigenetic regulation in B-cell maturation and its dysregulation in autoimmunity.KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2.Epigenomic Modifications Mediating Antibody Maturation.Generating and repairing genetically programmed DNA breaks during immunoglobulin class switch recombination.
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P2860
Combinatorial H3K9acS10ph histone modification in IgH locus S regions targets 14-3-3 adaptors and AID to specify antibody class-switch DNA recombination.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Combinatorial H3K9acS10ph hist ...... lass-switch DNA recombination.
@en
Combinatorial H3K9acS10ph hist ...... lass-switch DNA recombination.
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Combinatorial H3K9acS10ph hist ...... lass-switch DNA recombination.
@en
Combinatorial H3K9acS10ph hist ...... lass-switch DNA recombination.
@nl
prefLabel
Combinatorial H3K9acS10ph hist ...... lass-switch DNA recombination.
@en
Combinatorial H3K9acS10ph hist ...... lass-switch DNA recombination.
@nl
P2093
P2860
P1433
P1476
Combinatorial H3K9acS10ph hist ...... lass-switch DNA recombination.
@en
P2093
Clayton A White
Daniel C Tran
Egest J Pone
Guideng Li
Ken L Hayama
Paolo Casali
Tonika Lam
Zhenming Xu
P2860
P304
P356
10.1016/J.CELREP.2013.09.031
P577
2013-10-24T00:00:00Z