β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis. - Test2 - elhamkhani - TriplyDB

β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis.

β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis.

http://www.wikidata.org/entity/Q37634132

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Endothelial to Mesenchymal Transition (EndoMT) in the Pathogenesis of Human Fibrotic Diseases Vascular Remodelling and Mesenchymal Transition in Systemic Sclerosis Emerging Role and Therapeutic Implication of Wnt Signaling Pathways in Autoimmune Diseases MicroRNAs Regulating Signaling Pathways: Potential Biomarkers in Systemic Sclerosis Signaling in Fibrosis: TGF-β, WNT, and YAP/TAZ Converge The GSK-3 family as therapeutic target for myocardial diseases Recent advances in the genetics of systemic sclerosis: toward biological and clinical significance Versican in inflammation and tissue remodeling: the impact on lung disorders Non-Canonical Wnt Predominates in Activated Rat Hepatic Stellate Cells, Influencing HSC Survival and Paracrine Stimulation of Kupffer Cells Identification of cadherin 11 as a mediator of dermal fibrosis and possible role in systemic sclerosis.Morphogen pathways as molecular targets for the treatment of fibrosis in systemic sclerosis.The Wnt/β-catenin pathway in human fibrotic-like diseases and its eligibility as a therapeutic target.Sustained β-catenin activity in dermal fibroblasts promotes fibrosis by up-regulating expression of extracellular matrix protein-coding genes.Fibrosis in systemic sclerosis: common and unique pathobiology.Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury.Targeting miR-155 to Treat Experimental Scleroderma Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages.Paracrine Wnt1 Drives Interstitial Fibrosis without Inflammation by Tubulointerstitial Cross-Talk.Experimental inhibition of porcupine-mediated Wnt O-acylation attenuates kidney fibrosis.β-Catenin Stabilization in Skin Fibroblasts Causes Fibrotic Lesions by Preventing Adipocyte Differentiation of the Reticular Dermis Transcriptional profiling of rapamycin-treated fibroblasts from hypertrophic and keloid scars.Wnt4/β-catenin signaling in medullary kidney myofibroblasts Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing.Requirement for active glycogen synthase kinase-3β in TGF-β1 upregulation of connective tissue growth factor (CCN2/CTGF) levels in human gingival fibroblasts.Role of endothelial to mesenchymal transition in the pathogenesis of the vascular alterations in systemic sclerosis.Biomechanical regulation of mesenchymal cell function β-Catenin/CBP-Dependent Signaling Regulates TGF-β-Induced Epithelial to Mesenchymal Transition of Lens Epithelial Cells Morphogen pathways in systemic sclerosis.Stem cell signaling as a target for novel drug discovery: recent progress in the WNT and Hedgehog pathways.Understanding the origin, activation and regulation of matrix-producing myofibroblasts for treatment of fibrotic disease.Canonical Wnt signalling as a key regulator of fibrogenesis - implications for targeted therapies?Novel investigational agents for the treatment of scleroderma.Integrins and cadherins as therapeutic targets in fibrosis.Stroma as an Active Player in the Development of the Tumor Microenvironment.Fibrogenesis, novel lessons from animal models.Canonical Wnt signaling in systemic sclerosis.Recent advances in animal models of systemic sclerosis.Endothelial to mesenchymal transition (EndoMT) in the pathogenesis of Systemic Sclerosis-associated pulmonary fibrosis and pulmonary arterial hypertension. Myth or reality?Autophagy: controlling cell fate in rheumatic diseases.Epigenetic factors as drivers of fibrosis in systemic sclerosis.

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β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis.

http://www.wikidata.org/entity/Q37634132

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 10 February 2012

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis.

@en

β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis.

@nl

type

label

β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis.

@en

β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis.

@nl

prefLabel

β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis.

@en

β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis.

@nl

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ANNRHEUMDIS-2011-200568

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Annals of the Rheumatic Diseases

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β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis.

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Alfiya Akhmetshina

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Amelie Schramm

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Benoit de Crombrugghe

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Christian Beyer

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Clara Dees

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Jörg H W Distler

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Kolja Gelse

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Makoto Mark Taketo

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Oliver Distler

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Sonali Sonnylal

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Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

Wnt/beta-catenin signaling: components, mechanisms, and diseases

Cellular and molecular mechanisms of fibrosis

Increased expression of Wnt2 and SFRP4 in Tsk mouse skin: role of Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis

Wnt signalling in stem cells and cancer

Towards an integrated view of Wnt signaling in development

Functional Wnt signaling is increased in idiopathic pulmonary fibrosis

Point mutations in c-Myc uncouple neoplastic transformation from multiple other phenotypes in rat fibroblasts

beta-Catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds

Inhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis.

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761-767

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scholarly article

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10.1136/ANNRHEUMDIS-2011-200568

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5

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71

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2012-02-10T00:00:00Z

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221827065

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22328737

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3951949

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