Intracellular viral processing, not single-stranded DNA accumulation, is crucial for recombinant adeno-associated virus transduction.
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Adeno-associated Virus as a Mammalian DNA VectorParvovirus induced alterations in nuclear architecture and dynamicsAdeno-associated virus: from defective virus to effective vectorMutagenesis of adeno-associated virus type 2 capsid protein VP1 uncovers new roles for basic amino acids in trafficking and cell-specific transduction.Recombinant adeno-associated virus: efficient transduction of the rat VMH and clearance from blood.AAV exploits subcellular stress associated with inflammation, endoplasmic reticulum expansion, and misfolded proteins in models of cystic fibrosis.Activation of the cellular unfolded protein response by recombinant adeno-associated virus vectors.In vitro evaluation of a double-stranded self-complementary adeno-associated virus type2 vector in bone marrow stromal cells for bone healing.Gene therapy using adeno-associated virus vectorsSyntaxin 5-dependent retrograde transport to the trans-Golgi network is required for adeno-associated virus transduction.Functional analysis of the putative integrin recognition motif on adeno-associated virus 9.AAV vectors for cardiac gene transfer: experimental tools and clinical opportunities.Existence of transient functional double-stranded DNA intermediates during recombinant AAV transductionSelf-Complementary Adeno-Associated Virus Vectors Improve Transduction Efficiency of Corneal Endothelial Cells.Precise hit: adeno-associated virus in gene targeting.Investigation of the peak action wavelength of light-activated gene transductionBiological Therapies for Atrial Fibrillation: Ready for Prime Time?Recombinant adeno-associated virus transduction and integration.Recombinant adeno-associated virus utilizes host cell nuclear import machinery to enter the nucleusGene therapy strategies for cardiac electrical dysfunction.Recent advances in developing nucleic acid-based HBV therapy.Gene therapy for the treatment of Parkinson's disease: the nature of the biologics expands the future indicationsAdeno-associated virus type 2 capsids with externalized VP1/VP2 trafficking domains are generated prior to passage through the cytoplasm and are maintained until uncoating occurs in the nucleus.Impact of VP1-specific protein sequence motifs on adeno-associated virus type 2 intracellular trafficking and nuclear entry.Unique glycan signatures regulate adeno-associated virus tropism in the developing brain.Augmented transgene expression in transformed cells using a parvoviral hybrid vector.Low pH-dependent endosomal processing of the incoming parvovirus minute virus of mice virion leads to externalization of the VP1 N-terminal sequence (N-VP1), N-VP2 cleavage, and uncoating of the full-length genome.Single tyrosine mutation in AAV8 and AAV9 capsids is insufficient to enhance gene delivery to skeletal muscle and heart.Biophysical and ultrastructural characterization of adeno-associated virus capsid uncoating and genome release.Use of self-complementary adeno-associated virus serotype 2 as a tracer for labeling axons: implications for axon regenerationEx vivo intracoronary gene transfer of adeno-associated virus 2 leads to superior transduction over serotypes 8 and 9 in rat heart transplants.Enhancement of adeno-associated virus infection by mobilizing capsids into and out of the nucleolus.Freeze-thaw increases adeno-associated virus transduction of cells.Gene Therapy for Hemophilia: Progress to Date.Characterization of AAV vector particle stability at the single-capsid level.Development of a Click-Chemistry Reagent Compatible with Mass Cytometry.
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P2860
Intracellular viral processing, not single-stranded DNA accumulation, is crucial for recombinant adeno-associated virus transduction.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Intracellular viral processing ...... associated virus transduction.
@en
Intracellular viral processing ...... associated virus transduction.
@nl
type
label
Intracellular viral processing ...... associated virus transduction.
@en
Intracellular viral processing ...... associated virus transduction.
@nl
prefLabel
Intracellular viral processing ...... associated virus transduction.
@en
Intracellular viral processing ...... associated virus transduction.
@nl
P2093
P2860
P1433
P1476
Intracellular viral processing ...... associated virus transduction.
@en
P2093
Bernd Hauck
Katherine High
Weidong Xiao
P2860
P304
13678-13686
P356
10.1128/JVI.78.24.13678-13686.2004
P407
P577
2004-12-01T00:00:00Z