MLV integration site selection is driven by strong enhancers and active promoters.
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Applications of DNA integrating elements: Facing the bias bullyProgresses towards safe and efficient gene therapy vectorsLong-term correction of Sandhoff disease following intravenous delivery of rAAV9 to mouse neonatesHunting Viral Receptors Using Haploid CellsRetroviral integration: Site matters: Mechanisms and consequences of retroviral integration site selectionRetroviral DNA IntegrationComprehensive profiling of retroviral integration sites using target enrichment methods from historical koala samples without an assembled reference genomeStructural and sequencing analysis of local target DNA recognition by MLV integrase.Structural basis for spumavirus GAG tethering to chromatinNovel principles of gamma-retroviral insertional transcription activation in murine leukemia virus-induced end-stage tumors.Molecular mechanisms of retroviral integration site selection.Vector design influences hepatic genotoxicity after adeno-associated virus gene therapy.Key determinants of target DNA recognition by retroviral intasomes.DNA Physical Properties and Nucleosome Positions Are Major Determinants of HIV-1 Integrase SelectivityMutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish.A Multifunctional Mutagenesis System for Analysis of Gene Function in Zebrafish.Genome-wide Profiling Reveals Remarkable Parallels Between Insertion Site Selection Properties of the MLV Retrovirus and the piggyBac Transposon in Primary Human CD4(+) T Cells.Genetic Variation, Not Cell Type of Origin, Underlies the Majority of Identifiable Regulatory Differences in iPSCsAmplification, Next-generation Sequencing, and Genomic DNA Mapping of Retroviral Integration Sites.Gamma-Retrovirus Integration Marks Cell Type-Specific Cancer Genes: A Novel Profiling Tool in Cancer GenomicsGeIST: a pipeline for mapping integrated DNA elementsHIV-1 Integrates Widely throughout the Genome of the Human Blood Fluke Schistosoma mansoni.Towards a Safer, More Randomized Lentiviral Vector Integration Profile Exploring Artificial LEDGF Chimeras.LEDGF/p75 interacts with mRNA splicing factors and targets HIV-1 integration to highly spliced genes.The RUNX Genes as Conditional Oncogenes: Insights from Retroviral Targeting and Mouse Models.Common Viral Integration Sites Identified in Avian Leukosis Virus-Induced B-Cell Lymphomas.Structure of the Brd4 ET domain bound to a C-terminal motif from γ-retroviral integrases reveals a conserved mechanism of interaction.Genome-Wide Analysis of Transposon and Retroviral Insertions Reveals Preferential Integrations in Regions of DNA Flexibility.Sites of retroviral DNA integration: From basic research to clinical applicationsWhat Integration Sites Tell Us about HIV PersistenceRetrovirus Integration Database (RID): a public database for retroviral insertion sites into host genomesChromatin states shape insertion profiles of the piggyBac, Tol2 and Sleeping Beauty transposons and murine leukemia virus.Integration site and clonal expansion in human chronic retroviral infection and gene therapy.Viral Vectors: The Road to Reducing Genotoxicity.INSPIIRED: Quantification and Visualization Tools for Analyzing Integration Site Distributions.Integration site selection by retroviruses and transposable elements in eukaryotes.Hotspots of MLV integration in the hematopoietic tumor genomeRetroviral Scanning: Mapping MLV Integration Sites to Define Cell-specific Regulatory Regions.BET-independent MLV-based Vectors Target Away From Promoters and Regulatory Elements.Accumulation of long-term transcriptionally active integrated retroviral vectors in active promoters and enhancers.
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MLV integration site selection is driven by strong enhancers and active promoters.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 23 January 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
MLV integration site selection is driven by strong enhancers and active promoters.
@en
MLV integration site selection is driven by strong enhancers and active promoters.
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type
label
MLV integration site selection is driven by strong enhancers and active promoters.
@en
MLV integration site selection is driven by strong enhancers and active promoters.
@nl
prefLabel
MLV integration site selection is driven by strong enhancers and active promoters.
@en
MLV integration site selection is driven by strong enhancers and active promoters.
@nl
P2093
P2860
P50
P356
P1476
MLV integration site selection is driven by strong enhancers and active promoters.
@en
P2093
Andreas D Baxevanis
Derek E Gildea
Tyra G Wolfsberg
P2860
P304
P356
10.1093/NAR/GKT1399
P407
P577
2014-01-23T00:00:00Z