Disruption of the ASTN2/TRIM32 locus at 9q33.1 is a risk factor in males for autism spectrum disorders, ADHD and other neurodevelopmental phenotypes. - Test2 - elhamkhani - TriplyDB

Disruption of the ASTN2/TRIM32 locus at 9q33.1 is a risk factor in males for autism spectrum disorders, ADHD and other neurodevelopmental phenotypes.

Disruption of the ASTN2/TRIM32 locus at 9q33.1 is a risk factor in males for autism spectrum disorders, ADHD and other neurodevelopmental phenotypes.

http://www.wikidata.org/entity/Q37708396

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Brinp1(-/-) mice exhibit autism-like behaviour, altered memory, hyperactivity and increased parvalbumin-positive cortical interneuron density Discovery of Rare Mutations in Autism: Elucidating Neurodevelopmental Mechanisms The Immune Syntax Revisited: Opening New Windows on Language Evolution RhoGTPase Regulators Orchestrate Distinct Stages of Synaptic Development.Mice Lacking Brinp2 or Brinp3, or Both, Exhibit Behaviors Consistent with Neurodevelopmental Disorders.The neural stem cell fate determinant TRIM32 regulates complex behavioral traits.Cerebellar Development and Autism Spectrum Disorder in Tuberous Sclerosis Complex.Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.Genome-wide significant loci for addiction and anxiety Hoarding in Children and Adolescents with Obsessive-Compulsive Disorder.Detection of TRIM32 deletions in LGMD patients analyzed by a combined strategy of CGH array and massively parallel sequencing A high-resolution copy-number variation resource for clinical and population genetics.CNV analysis in Chinese children of mental retardation highlights a sex differentiation in parental contribution to de novo and inherited mutational burdens Indexing Effects of Copy Number Variation on Genes Involved in Developmental Delay.Uncovering obsessive-compulsive disorder risk genes in a pediatric cohort by high-resolution analysis of copy number variation.Novel genetic loci associated with hippocampal volume.The complex genetics of gait speed: genome-wide meta-analysis approach RNA sequencing of transformed lymphoblastoid cells from siblings discordant for autism spectrum disorders reveals transcriptomic and functional alterations: Evidence for sex-specific effects.Regulation of neuronal migration, an emerging topic in autism spectrum disorders.Genetics of attention-deficit/hyperactivity disorder: an update.Repurposing a pore: highly conserved perforin-like proteins with alternative mechanisms.Expression of the Parkinson's Disease-Associated Gene Alpha-Synuclein is Regulated by the Neuronal Cell Fate Determinant TRIM32.An update on the comorbidity of ADHD and ASD: a focus on clinical management.Rare copy number variants are common in young children with autism spectrum disorder.Polymorphisms within ASTN2 gene are associated with age at onset of Alzheimer's disease.Cleave but not leave: Astrotactin proteins in development and disease.Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development.The role of ASTN2 variants in childhood and adult ADHD, comorbid disorders and associated personality traits.Next Generation Sequencing and the Child and Youth Psychiatrist.Fundamental Elements in Autism: From Neurogenesis and Neurite Growth to Synaptic Plasticity.Genetic testing including targeted gene panel in a diverse clinical population of children with autism spectrum disorder: Findings and implications.The morphometric co-atrophy networking of schizophrenia, autistic and obsessive spectrum disorders.Copy Number Variation Analysis of 100 Twin Pairs Enriched for Neurodevelopmental Disorders.Deletion of TRIM32 protects mice from anxiety- and depression-like behaviors under mild stress.Association of Autism Spectrum Disorder with Obsessive-Compulsive and Attention-Deficit/Hyperactivity Traits and Response Inhibition in a Community Sample.Intramembrane Proteolysis of Astrotactins.Brain-expressed exons under purifying selection are enriched for de novo mutations in autism spectrum disorder.Chromosomal microarray analysis in the genetic evaluation of 279 patients with syndromic obesity.Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons

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Disruption of the ASTN2/TRIM32 locus at 9q33.1 is a risk factor in males for autism spectrum disorders, ADHD and other neurodevelopmental phenotypes.

http://www.wikidata.org/entity/Q37708396

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 30 December 2013

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Disruption of the ASTN2/TRIM32 ...... neurodevelopmental phenotypes.

@en

Disruption of the ASTN2/TRIM32 ...... neurodevelopmental phenotypes.

@nl

type

label

Disruption of the ASTN2/TRIM32 ...... neurodevelopmental phenotypes.

@en

Disruption of the ASTN2/TRIM32 ...... neurodevelopmental phenotypes.

@nl

prefLabel

Disruption of the ASTN2/TRIM32 ...... neurodevelopmental phenotypes.

@en

Disruption of the ASTN2/TRIM32 ...... neurodevelopmental phenotypes.

@nl

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Human Molecular Genetics

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Disruption of the ASTN2/TRIM32 ...... neurodevelopmental phenotypes.

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Abdul Noor

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Anath C Lionel

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Andrea K Vaags

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Ann C White

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Anna M Nardone

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Bai-Lin Wu

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Bob Argiropoulos

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Bridget A Fernandez

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Carlo Poggiani

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Caroline Mackie Ogilvie

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scholarly article

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10.1093/HMG/DDT669

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10

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23

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Andrew D. Paterson

Russell Schachar

Sebastiano Antonino Musumeci

Michael E. Talkowski

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2013-12-30T00:00:00Z

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24381304

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