Proximity-enabled protein crosslinking through genetically encoding haloalkane unnatural amino acids.
about
Bioconjugation of therapeutic proteins and enzymes using the expanded set of genetically encoded amino acids.Genetically encoding photoswitchable click amino acids in Escherichia coli and mammalian cellsSortase A-mediated crosslinked short-chain dehydrogenases/reductases as novel biocatalysts with improved thermostability and catalytic efficiencyEnhancing protein stability with extended disulfide bonds.Stabilization of Bacillus circulans xylanase by combinatorial insertional fusion to a thermophilic host protein.In Situ Formation of an Azo Bridge on Proteins Controllable by Visible Light.Structural insight into the activation of a class B G-protein-coupled receptor by peptide hormones in live human cells.Genetically encoding new bioreactivity.Synthesis and Incorporation of Unnatural Amino Acids To Probe and Optimize Protein Bioconjugations.Bioinspired strategy for the ribosomal synthesis of thioether-bridged macrocyclic peptides in bacteria.Genetically encoding an electrophilic amino acid for protein stapling and covalent binding to native receptors.Engineering the Genetic Code in Cells and Animals: Biological Considerations and Impacts.Spontaneous and specific chemical cross-linking in live cells to capture and identify protein interactions.Enzyme stabilization via computationally guided protein stapling.Proximity-Triggered Covalent Stabilization of Low-Affinity Protein Complexes In Vitro and In Vivo.Disulfide Bond Mimetics: Strategies and Challenges.Playing with the molecules of life.Computing with synthetic protocells.Protein Crosslinking by Genetically Encoded Noncanonical Amino Acids with Reactive Aryl Carbamate Side Chains.Genetic Incorporation of a Reactive Isothiocyanate Group into Proteins.Genetically Encoding Fluorosulfate-l-tyrosine To React with Lysine, Histidine, and Tyrosine via SuFEx in Proteins in Vivo.Oxidation-induced generation of a mild electrophile for proximity-enhanced protein-protein crosslinking.Proximitäts-vermittelte kovalente Stabilisierung niedrig-affiner Proteinkomplexe in vitro und in vivo
P2860
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P2860
Proximity-enabled protein crosslinking through genetically encoding haloalkane unnatural amino acids.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 21 January 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Proximity-enabled protein cros ...... oalkane unnatural amino acids.
@en
Proximity-enabled protein cros ...... oalkane unnatural amino acids.
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type
label
Proximity-enabled protein cros ...... oalkane unnatural amino acids.
@en
Proximity-enabled protein cros ...... oalkane unnatural amino acids.
@nl
prefLabel
Proximity-enabled protein cros ...... oalkane unnatural amino acids.
@en
Proximity-enabled protein cros ...... oalkane unnatural amino acids.
@nl
P2093
P2860
P356
P1476
Proximity-enabled protein cros ...... loalkane unnatural amino acids
@en
P2093
David J Burban
Haiyan Ren
Patricia A Jennings
Vanessa K Lacey
Zheng Xiang
P2860
P304
P356
10.1002/ANIE.201308794
P407
P577
2014-01-21T00:00:00Z