DhhP, a cyclic di-AMP phosphodiesterase of Borrelia burgdorferi, is essential for cell growth and virulence
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Cyclic di-AMP targets the cystathionine beta-synthase domain of the osmolyte transporter OpuCDetection of cyclic di-AMP using a competitive ELISA with a unique pneumococcal cyclic di-AMP binding protein.An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence.Chemical proteomics reveals a second family of cyclic-di-AMP hydrolasesIdentification of bromophenol thiohydantoin as an inhibitor of DisA, a c-di-AMP synthase, from a 1000 compound library, using the coralyne assay.Intracellular Concentrations of Borrelia burgdorferi Cyclic Di-AMP Are Not Changed by Altered Expression of the CdaA SynthaseFunctional Analysis of a c-di-AMP-specific Phosphodiesterase MsPDE from Mycobacterium smegmatisDeveloping a Novel Gene-Delivery Vector System Using the Recombinant Fusion Protein of Pseudomonas Exotoxin A and Hyperthermophilic Archaeal Histone HPhA.The Characterization of Escherichia coli CpdB as a Recombinant Protein Reveals that, besides Having the Expected 3´-Nucleotidase and 2´,3´-Cyclic Mononucleotide Phosphodiesterase Activities, It Is Also Active as Cyclic Dinucleotide PhosphodiesteraseFunctional analysis of the sporulation-specific diadenylate cyclase CdaS in Bacillus thuringiensisRNA-Seq of Borrelia burgdorferi in Multiple Phases of Growth Reveals Insights into the Dynamics of Gene Expression, Transcriptome Architecture, and Noncoding RNAsOuter surface protein OspC is an antiphagocytic factor that protects Borrelia burgdorferi from phagocytosis by macrophages.Structural and Biochemical Insight into the Mechanism of Rv2837c from Mycobacterium tuberculosis as a c-di-NMP PhosphodiesteraseNuclease-Resistant c-di-AMP Derivatives That Differentially Recognize RNA and Protein ReceptorsBorrelia burgdorferi elongation factor EF-Tu is an immunogenic protein during Lyme borreliosis.A jack of all trades: the multiple roles of the unique essential second messenger cyclic di-AMP.Too much of a good thing: regulated depletion of c-di-AMP in the bacterial cytoplasm.Cyclic dinucleotide (c-di-GMP, c-di-AMP, and cGAMP) signalings have come of age to be inhibited by small molecules.c-di-AMP: An Essential Molecule in the Signaling Pathways that Regulate the Viability and Virulence of Gram-Positive Bacteria.New Insights into the Cyclic Di-adenosine Monophosphate (c-di-AMP) Degradation Pathway and the Requirement of the Cyclic Dinucleotide for Acid Stress Resistance in Staphylococcus aureus.Regulation of oxidative response and extracellular polysaccharide synthesis by a diadenylate cyclase in Streptococcus mutans.Cyclic di-AMP mediates biofilm formation.Identification of the Components Involved in Cyclic Di-AMP Signaling in Mycoplasma pneumoniae.Genetic Manipulation of Borrelia Spp.Regulation of Gene and Protein Expression in the Lyme Disease Spirochete.Cyclic-di-AMP synthesis by the diadenylate cyclase CdaA is modulated by the peptidoglycan biosynthesis enzyme GlmM in Lactococcus lactis.Structural and functional studies of pyruvate carboxylase regulation by cyclic di-AMP in lactic acid bacteria.Generation of Conditional Mutants in Borrelia burgdorferi.Structural and biochemical characterization of the catalytic domains of GdpP reveals a unified hydrolysis mechanism for the DHH/DHHA1 phosphodiesterase.Homeostasis of Second Messenger Cyclic-di-AMP Is Critical for Cyanobacterial Fitness and Acclimation to Abiotic Stress.Biological and Biochemical Roles of Two Distinct Cyclic Dimeric Adenosine 3',5'-Monophosphate- Associated Phosphodiesterases in
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DhhP, a cyclic di-AMP phosphodiesterase of Borrelia burgdorferi, is essential for cell growth and virulence
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 February 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
DhhP, a cyclic di-AMP phosphod ...... for cell growth and virulence
@en
DhhP, a cyclic di-AMP phosphod ...... for cell growth and virulence.
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type
label
DhhP, a cyclic di-AMP phosphod ...... for cell growth and virulence
@en
DhhP, a cyclic di-AMP phosphod ...... for cell growth and virulence.
@nl
prefLabel
DhhP, a cyclic di-AMP phosphod ...... for cell growth and virulence
@en
DhhP, a cyclic di-AMP phosphod ...... for cell growth and virulence.
@nl
P2093
P2860
P356
P1476
DhhP, a cyclic di-AMP phosphod ...... for cell growth and virulence
@en
P2093
Gavin B Lawlis
Jun-Jie Zhang
Meiping Ye
X Frank Yang
Yongliang Lou
P2860
P304
P356
10.1128/IAI.00030-14
P407
P577
2014-02-24T00:00:00Z