Targeting sphingolipid metabolism in head and neck cancer: rational therapeutic potentials. - Test2 - elhamkhani - TriplyDB

Targeting sphingolipid metabolism in head and neck cancer: rational therapeutic potentials.

Targeting sphingolipid metabolism in head and neck cancer: rational therapeutic potentials.

http://www.wikidata.org/entity/Q37718254

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The impact of sphingosine kinase-1 in head and neck cancer.LCL124, a cationic analog of ceramide, selectively induces pancreatic cancer cell death by accumulating in mitochondria.Many ceramides.Development of small-molecule inhibitors of sphingosine-1-phosphate signaling Ceramide--antiestrogen nanoliposomal combinations--novel impact of hormonal therapy in hormone-insensitive breast cancer.C2-ceramide induces cell death and protective autophagy in head and neck squamous cell carcinoma cells.Induction of apoptosis in prostate cancer cells by the novel ceramidase inhibitor ceranib-2.Roles of ceramide synthase and ceramide clearence genes in nilotinib-induced cell death in chronic myeloid leukemia cells.Ceramide in cystic fibrosis: a potential new target for therapeutic intervention.Sphingosine but not sphingosine-1-phosphate stimulates suicidal erythrocyte death.

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Targeting sphingolipid metabolism in head and neck cancer: rational therapeutic potentials.

http://www.wikidata.org/entity/Q37718254

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on May 2010

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Targeting sphingolipid metabol ...... tional therapeutic potentials.

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Targeting sphingolipid metabol ...... tional therapeutic potentials.

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type

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Targeting sphingolipid metabol ...... tional therapeutic potentials.

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Targeting sphingolipid metabol ...... tional therapeutic potentials.

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Targeting sphingolipid metabol ...... tional therapeutic potentials.

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Targeting sphingolipid metabol ...... tional therapeutic potentials.

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Expert Opinion on Therapeutic Targets

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Targeting sphingolipid metabol ...... tional therapeutic potentials.

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James S Norris

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Joseph C Cheng

http://www.w3.org/2001/XMLSchema#string

Lorianne S Turner

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Saeed Elojeimy

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Stanley R Hoffman

http://www.w3.org/2001/XMLSchema#string

Thomas H Beckham

http://www.w3.org/2001/XMLSchema#string

Xiang Liu

http://www.w3.org/2001/XMLSchema#string

P2860

PP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulum

The complex life of simple sphingolipids

FTY720 inhibits ceramide synthases and up-regulates dihydrosphingosine 1-phosphate formation in human lung endothelial cells

Roles of bioactive sphingolipids in cancer biology and therapeutics

Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1

Ceramide-1-phosphate promotes cell survival through activation of the phosphatidylinositol 3-kinase/protein kinase B pathway

Targeting PI3K signalling in cancer: opportunities, challenges and limitations

Discovery and evaluation of inhibitors of human sphingosine kinase.

Killing cancer cells by poly-drug elevation of ceramide levels: a hypothesis whose time has come?

Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer.

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529-539

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scholarly article

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10.1517/14728221003752768

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2861896

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