The role of population PK-PD modelling in paediatric clinical research.
about
Recommendations and evidence for reporting items in pediatric clinical trial protocols and reports: two systematic reviewsDrug-induced renal damage in preterm neonates: state of the art and methods for early detectionPharmacologic management of the opioid neonatal abstinence syndromeNeonatal clinical pharmacologyEducational paper: do we need neonatal clinical pharmacologists?Persistent pharmacokinetic challenges to pediatric drug developmentFirst dose in neonates: are juvenile mice, adults and in vitro-in silico data predictive of neonatal pharmacokinetics of fluconazole.METFORMIN: an efficacy, safety and pharmacokinetic study on the short-term and long-term use in obese children and adolescents - study protocol of a randomized controlled study.Clinical pharmacology in neonates: small size, huge variabilityClinical pharmacological studies in children: From exploratory towards confirmation driven methodology.Towards evidence-based dosing regimens in children on the basis of population pharmacokinetic pharmacodynamic modelling.Pediatric microdose study of [(14)C]paracetamol to study drug metabolism using accelerated mass spectrometry: proof of conceptBridging the gap: a review of dose investigations in paediatric investigation plansPopulation pharmacokinetics of gentamicin and dosing optimization for infantsPaediatric pharmacokinetics: key considerations.The effect of malnutrition on the pharmacokinetics and virologic outcomes of lopinavir, efavirenz and nevirapine in food insecure HIV-infected children in Tororo, UgandaComparable liraglutide pharmacokinetics in pediatric and adult populations with type 2 diabetes: a population pharmacokinetic analysis.Developmental changes rather than repeated administration drive paracetamol glucuronidation in neonates and infants.Prospective Evaluation of a Model-Based Dosing Regimen for Amikacin in Preterm and Term Neonates in Clinical PracticeBusulfan dosing algorithm and sampling strategy in stem cell transplantation patients.Pharmacokinetics of tralokinumab in adolescents with asthma: implications for future dosing.Pharmacological treatment of neonatal pain: in search of a new equipoiseClinical pharmacology in neonates and young infants: the benefit of a population-tailored approach.Simultaneous pharmacokinetic modeling of gentamicin, tobramycin and vancomycin clearance from neonates to adults: towards a semi-physiological function for maturation in glomerular filtrationTowards Rational Dosing Algorithms for Vancomycin in Neonates and Infants Based on Population Pharmacokinetic Modeling.Pain in Intellectually Disabled Children: Towards Evidence-Based Pharmacotherapy?External Evaluation of Population Pharmacokinetic Models of Vancomycin in Neonates: The transferability of published models to different clinical settings.Population pharmacokinetics of abacavir in infants, toddlers and children.Assessment of juvenile pigs to serve as human pediatric surrogates for preclinical formulation pharmacokinetic testing.Development of a population pharmacokinetic model of prucalopride in children with functional constipation.Drug Development for Pediatric Populations: Regulatory Aspects.Pharmacokinetics and pharmacodynamics of intravenous acetaminophen in neonates.Prediction of morphine clearance in the paediatric population : how accurate are the available pharmacokinetic models?Population pharmacometrics in support of analgesics studies.Methods for pharmacokinetic analysis in young children.Tailored tools to improve pharmacotherapy in infants.Ethics of drug research in the pediatric intensive care unit.Optimal design in pediatric pharmacokinetic and pharmacodynamic clinical studies.Neonatal medicines research: challenges and opportunities.Pharmacokinetics in neonatal prescribing: evidence base, paradigms and the future.
P2860
Q26783200-820C3ADF-C9F4-43E3-A76B-86F6CB8E2237Q26849339-E62FCD01-9266-4167-AA74-6E880F9F6555Q26863355-AC23A0ED-3251-4782-ADBC-AE7EF3670735Q26992019-F7BF6A43-FDA8-4AF4-BE4E-4EE04F9E3545Q27009662-8FE23647-62DE-42F1-BE58-41CC7CB4156EQ27023912-7B4CD0F8-31FA-49BC-879C-57CDB7FD6423Q30844731-5651784E-F6AA-48F4-9802-62498176BBA7Q33740123-64317FD6-D98C-41F4-A962-C45E236DA3ECQ33950874-D8BBAAA3-C00D-4173-9E10-1D01FE77CCD8Q34093287-DDBC2363-5D83-4BBD-85A1-1787B89C0416Q34393200-E30DB868-5F85-410A-9EA5-08C815E3BE2AQ34422598-B0033CD3-E287-4854-A889-677EF1C84DB4Q34554486-59160C33-3294-4888-9015-5B6ECA346F69Q34923469-829FD9CC-5AA2-4B3C-A4F7-87DCEFA6D273Q35135940-B8DB6AAA-F333-4EC3-B2FB-9B1ED4F26DC4Q35154032-DF9B3336-E635-463E-84ED-708C4CD6941BQ35666210-FE82B14B-517C-4D89-B955-98657A9C083AQ35941220-76A8665B-628F-4937-944A-0EF8384632A4Q36075844-ED6F53A2-D9E8-4378-A38C-99D1E940D7E6Q36125427-73BD8F1B-F8D5-4FF2-AD58-BF9370CABB0EQ36410129-CB57C5CB-A76B-410B-9CAB-D84008EE6DC2Q36452341-CFE93063-79B7-45C4-B9BE-748A226E1B30Q36452352-6C48547F-9669-40EC-9DAC-10AB57FFB729Q36568925-1FCF4330-BD2E-4514-8336-98869AAF1CCAQ36571794-450C43AC-87B4-4F19-AA54-C5E4A723876FQ36621626-68D858C5-7032-408F-80C8-4A7D2CD3909DQ36729959-D735C8CC-6B92-4CC4-84A4-8A17A8BDAB1EQ36948138-66D05634-2B45-4EAD-94CB-CE18BF12D7D7Q36951897-EED8919D-2A69-463A-8A9F-D63673506A2CQ37421978-11C44244-0FC4-4A86-A578-47CA431C4866Q37666706-45450328-2380-484F-A935-D311F7669B66Q37960126-F4F47CD5-7311-4AA2-B670-8BBF46ACFA3FQ38047202-6C731FAE-85A9-4DCC-8416-124C601AFE29Q38175171-F5D948F1-35CE-41C9-8C0C-BC5B9810CCC3Q38187157-EA7A498B-ED0D-4F02-997B-F762B0F744FEQ38222870-99A8583F-AEF6-4354-B339-A6FBB04A85FCQ38263726-B03876CA-6BDD-424A-B5A9-110D0A245116Q38315070-4B6DAB42-2B4E-4AF5-9B6A-FA9755814FBAQ38469763-BFDB24B2-7AED-4054-8E39-9FEB20654E34Q38563371-8ABA0538-14E2-41A1-AA9A-EA0BC4DE4DC1
P2860
The role of population PK-PD modelling in paediatric clinical research.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 26 March 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The role of population PK-PD modelling in paediatric clinical research.
@en
The role of population PK-PD modelling in paediatric clinical research.
@nl
type
label
The role of population PK-PD modelling in paediatric clinical research.
@en
The role of population PK-PD modelling in paediatric clinical research.
@nl
prefLabel
The role of population PK-PD modelling in paediatric clinical research.
@en
The role of population PK-PD modelling in paediatric clinical research.
@nl
P2093
P2860
P1476
The role of population PK-PD modelling in paediatric clinical research
@en
P2093
Chiara Piana
Elke H J Krekels
Meindert Danhof
Roosmarijn F W De Cock
P2860
P2888
P356
10.1007/S00228-009-0782-9
P478
67 Suppl 1
P577
2010-03-26T00:00:00Z