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How, with whom and when: an overview of CD147-mediated regulatory networks influencing matrix metalloproteinase activityProstate cancer relevant antigens and enzymes for targeted drug deliveryThe altered glucose metabolism in tumor and a tumor acidic microenvironment associated with extracellular matrix metalloproteinase inducer and monocarboxylate transportersSelecting Targets for Tumor Imaging: An Overview of Cancer-Associated Membrane ProteinsHypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H(+) symportersThe roles of CD147 and/or cyclophilin A in kidney diseasesCD147, CD44, and the epidermal growth factor receptor (EGFR) signaling pathway cooperate to regulate breast epithelial cell invasiveness.Ultra-sensitive liquid biopsy of circulating extracellular vesicles using ExoScreenEvaluation of MCT1, MCT4 and CD147 Genes in Peripheral Blood Cells of Breast Cancer Patients and Their Potential Use as Diagnostic and Prognostic Markers.The level of CD147 expression correlates with cyclophilin-induced signalling and chemotaxis.Full-length soluble CD147 promotes MMP-2 expression and is a potential serological marker in detection of hepatocellular carcinomaEMMPRIN is an independent negative prognostic factor for patients with astrocytic glioma.Evaluation of (89)Zr-labeled human anti-CD147 monoclonal antibody as a positron emission tomography probe in a mouse model of pancreatic cancer.Upregulation of CD147 promotes cell invasion, epithelial-to-mesenchymal transition and activates MAPK/ERK signaling pathway in colorectal cancer.Epitope mapping of metuximab on CD147 using phage display and molecular docking.Intracellular Acidosis Promotes Mitochondrial Apoptosis Pathway: Role of EMMPRIN Down-regulation via Specific Single-chain Fv IntrabodyEvidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts.CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors.Relationship between CD147 and expression of amino acid transporters (LAT1 and ASCT2) in patients with pancreatic cancer.Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN.Disruption of BASIGIN decreases lactic acid export and sensitizes non-small cell lung cancer to biguanides independently of the LKB1 statusEMMPRIN/CD147 is a novel coreceptor of VEGFR-2 mediating its activation by VEGF.The Cyclophilin A-CD147 complex promotes the proliferation and homing of multiple myeloma cells.Extracellular Antibody Drug Conjugates Exploiting the Proximity of Two ProteinsBasigin-mediated redistribution of CD98 promotes cell spreading and tumorigenicity in hepatocellular carcinoma.A novel anti-EMMPRIN function-blocking antibody reduces T cell proliferation and neurotoxicity: relevance to multiple sclerosisKnock out of the BASIGIN/CD147 chaperone of lactate/H+ symporters disproves its pro-tumour action via extracellular matrix metalloproteases (MMPs) induction.New insights into germ cell migration and survival/apoptosis in spermatogenesis: Lessons from CD147.EMMPRIN regulates tumor growth and metastasis by recruiting bone marrow-derived cells through paracrine signaling of SDF-1 and VEGF.Obesity-driven inflammation and cancer risk: role of myeloid derived suppressor cells and alternately activated macrophages.An epitope-specific novel anti-EMMPRIN polyclonal antibody inhibits tumor progression.Emmprin and KSHV: new partners in viral cancer pathogenesis.Interaction of KLF6 and Sp1 regulates basigin-2 expression mediated proliferation, invasion and metastasis in hepatocellular carcinoma.HAb18G/CD147 promotes pSTAT3-mediated pancreatic cancer development via CD44s.Extracellular matrix metalloproteinase inducer (EMMPRIN) expression correlates positively with active angiogenesis and negatively with basic fibroblast growth factor expression in epithelial ovarian cancer.F-Box Protein FBXO22 Mediates Polyubiquitination and Degradation of CD147 to Reverse Cisplatin Resistance of Tumor Cells.Epidermal CD147 expression plays a key role in IL-22-induced psoriatic dermatitis.CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming.CD147 regulates extrinsic apoptosis in spermatocytes by modulating NFκB signaling pathways.Zirconium-89 labeled antibodies: a new tool for molecular imaging in cancer patients.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Cancer-related issues of CD147.
@en
Cancer-related issues of CD147.
@nl
type
label
Cancer-related issues of CD147.
@en
Cancer-related issues of CD147.
@nl
prefLabel
Cancer-related issues of CD147.
@en
Cancer-related issues of CD147.
@nl
P2093
P1476
Cancer-related issues of CD147
@en
P2093
Daniela Eggle
Hannes Stockinger
Stefan Klostermann
Ulrich H Weidle
Werner Scheuer
P304
P577
2010-05-01T00:00:00Z