Bruton's tyrosine kinase as a molecular target in treatment of leukemias and lymphomas as well as inflammatory disorders and autoimmunity.

Bruton's tyrosine kinase as a molecular target in treatment of leukemias and lymphomas as well as inflammatory disorders and autoimmunity.

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http://www.wikidata.org/entity/Q37787243
Insights into the conformational flexibility of Bruton's tyrosine kinase from multiple ligand complex structuresRegulatory phosphorylation of Ikaros by Bruton's tyrosine kinaseBruton's TK inhibitors: structural insights and evolution of clinical candidates.A unique role for ITK in survival of invariant NKT cells associated with the p53-dependent pathway in mice.Toll-like receptor 4-, 7-, and 8-activated myeloid cells from patients with X-linked agammaglobulinemia produce enhanced inflammatory cytokines.Role of Bruton's tyrosine kinase in myeloma cell migration and induction of bone diseaseTyrosine kinase inhibitors as potential drugs for B-cell lymphoid malignancies and autoimmune disorders.The role of microparticles in the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus.Pharmacodynamic considerations of small molecule targeted therapy for treating B-cell malignancies in the elderly.Inhibitors of Bruton's Tyrosine Kinase (Btk) May Treat Inflammation, Immunological Disorders, and Cancer.Development of a pharmacodynamic assay based on PLCγ2 phosphorylation for quantifying spleen tyrosine kinase (SYK)-Bruton's tyrosine kinase (BTK) signaling.Inducing apoptosis in chemotherapy-resistant B-lineage acute lymphoblastic leukaemia cells by targeting HSPA5, a master regulator of the anti-apoptotic unfolded protein response signalling network.
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Bruton's tyrosine kinase as a molecular target in treatment of leukemias and lymphomas as well as inflammatory disorders and autoimmunity.

Item
http://www.wikidata.org/entity/Q37787243
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 10 September 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Bruton's tyrosine kinase as a ...... ry disorders and autoimmunity.
@en
Bruton's tyrosine kinase as a ...... ry disorders and autoimmunity.
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type
label
Bruton's tyrosine kinase as a ...... ry disorders and autoimmunity.
@en
Bruton's tyrosine kinase as a ...... ry disorders and autoimmunity.
@nl
prefLabel
Bruton's tyrosine kinase as a ...... ry disorders and autoimmunity.
@en
Bruton's tyrosine kinase as a ...... ry disorders and autoimmunity.
@nl
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P1476
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P2860
P304
P31
P356
P407
P433
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Bruton's tyrosine kinase as a ...... ry disorders and autoimmunity.
@en
P2093
P2860
P304
P31
P356
10.1517/13543776.2010.517750
P407
P433
P478
P50
P577
P698
P921