Folding at the birth of the nascent chain: coordinating translation with co-translational folding.
about
Strong purifying selection at synonymous sites in D. melanogasterRedundancy of the genetic code enables translational pausingCo- and Post-Translational Protein Folding in the ERDoes constructive neutral evolution play an important role in the origin of cellular complexity? Making sense of the origins and uses of biological complexityInterdomain contacts control folding of transcription factor RfaH.The imprint of codons on protein structure.Folding of a single domain protein entering the endoplasmic reticulum precedes disulfide formation.The effect of tRNA levels on decoding times of mRNA codons.Protein folding at the exit tunnel.tRNA concentration fine tunes protein solubility.Mechanisms of cellular proteostasis: insights from single-molecule approachesMisfolded proteins: from little villains to little helpers in the fight against cancer.Ribosome pausing, arrest and rescue in bacteria and eukaryotes.Molecular engineering of secretory machinery components for high-level secretion of proteins in Bacillus species.Optimization of translation profiles enhances protein expression and solubilityHow Co-translational Folding of Multi-domain Protein Is Affected by Elongation Schedule: Molecular Simulations.Local slowdown of translation by nonoptimal codons promotes nascent-chain recognition by SRP in vivo.Secondary Structure across the Bacterial Transcriptome Reveals Versatile Roles in mRNA Regulation and FunctionGenome-Wide and Experimental Resolution of Relative Translation Elongation Speed at Individual Gene Level in Human CellsOrganization of the multiaminoacyl-tRNA synthetase complex and the cotranslational protein folding.Role of mRNA structure in the control of protein foldingA novel approach to recovery of function of mutant proteins by slowing down translation.Integrated in vivo and in vitro nascent chain profiling reveals widespread translational pausing.Translating mRNAs strongly correlate to proteins in a multivariate manner and their translation ratios are phenotype specific.Modulated Expression of Specific tRNAs Drives Gene Expression and Cancer Progression.Structural characterization of the interaction of α-synuclein nascent chains with the ribosomal surface and trigger factorInterrelation between protein synthesis, proteostasis and life spanProtein folding on the ribosome studied using NMR spectroscopy.The various facets of the protein-folding activity of the ribosome.The ribosome as a hub for protein quality control.Formyl-methionine as a degradation signal at the N-termini of bacterial proteins.Synonymous Codons Direct Cotranslational Folding toward Different Protein Conformations.Emerging roles of tRNA in adaptive translation, signalling dynamics and disease.Mapping the non-standardized biases of ribosome profiling.Hepatitis A virus adaptation to cellular shutoff is driven by dynamic adjustments of codon usage and results in the selection of populations with altered capsids.Computational analysis of nascent peptides that induce ribosome stalling and their proteomic distribution in Saccharomyces cerevisiae.How and why does Dia1 mRNA localize?The Yin and Yang of Codon Usage.Length-dependent translation initiation benefits the functional proteome of human cells.Rewiring host activities for synthetic circuit production: a translation view.
P2860
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P2860
Folding at the birth of the nascent chain: coordinating translation with co-translational folding.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Folding at the birth of the na ...... with co-translational folding.
@en
Folding at the birth of the na ...... with co-translational folding.
@nl
type
label
Folding at the birth of the na ...... with co-translational folding.
@en
Folding at the birth of the na ...... with co-translational folding.
@nl
prefLabel
Folding at the birth of the na ...... with co-translational folding.
@en
Folding at the birth of the na ...... with co-translational folding.
@nl
P1476
Folding at the birth of the na ...... with co-translational folding.
@en
P2093
Zoya Ignatova
P356
10.1016/J.SBI.2010.10.008
P50
P577
2010-11-24T00:00:00Z