about
A crystal structure-guided rational design switching non-carbohydrate inhibitors' specificity between two β-GlcNAcase homologsNovel Fluorescence Arginine Analogue as a Sensor for Direct Identification and Imaging of Nitric Oxide Synthase-like Enzymes in PlantsThiadiazole: a new family of intercalative photonuclease with electron transfer and radical mechanisms.Novel 2-aminothiazonaphthalimides as visible light activatable photonucleases: effects of intercalation, heterocyclic-fused area and side chains.Acenaphtho[1,2-b]pyrrole derivatives as new family of intercalators: various DNA binding geometry and interesting antitumor capacity.Fluorescent imaging of acute mercuric chloride exposure on cultured human kidney tubular epithelial cells.Bright, Stable, and Biocompatible Organic Fluorophores Absorbing/Emitting in the Deep Near-Infrared Spectral Region.Visible study of mercuric ion and its conjugate in living cells of mammals and plants.A rhodamine-based Hg2+ sensor with high selectivity and sensitivity in aqueous solution: a NS2-containing receptor.Development of Unsymmetrical Dyads As Potent Noncarbohydrate-Based Inhibitors against Human β-N-Acetyl-d-hexosaminidaseQuantitatively mapping cellular viscosity with detailed organelle information via a designed PET fluorescent probe.Unprecedented laser action from energy transfer in multichromophoric BODIPY cassettes.Discrimination and classification of ginsenosides and ginsengs using bis-boronic acid receptors in dynamic multicomponent indicator displacement sensor arrays.SoNar, a Highly Responsive NAD+/NADH Sensor, Allows High-Throughput Metabolic Screening of Anti-tumor Agents.A Synthetic DNA-Binding Domain Guides Distinct Chromatin-Modifying Small Molecules to Activate an Identical Gene Network.Photocalibrated NO Release from N-Nitrosated Napthalimides upon One-Photon or Two-Photon Irradiation.Naphthalimides induce G(2) arrest through the ATM-activated Chk2-executed pathway in HCT116 cells.Recent progress of highly efficient in vivo biological screening for novel agrochemicals in China.cis-Configuration: a new tactic/rationale for neonicotinoid molecular design.Advanced research on cis-Neonicotinoids.Rationally designed multitarget anticancer agents.Fluorescence imaging of metal ions implicated in diseases.Discovery of a novel family of polycyclic aromatic molecules with unique reactivity and members valuable for fluorescent sensing and medicinal chemistry.China: forward to the green pesticides via a basic research program.3B, a novel photosensitizer, inhibits glycolysis and inflammation via miR-155-5p and breaks the JAK/STAT3/SOCS1 feedback loop in human breast cancer cells.Ammonium salt modified mesoporous silica nanoparticles for dual intracellular-responsive gene delivery.Structurally Rigid 9-Amino-benzo[c]cinnoliniums Make Up a Class of Compact and Large Stokes-Shift Fluorescent Dyes for Cell-Based Imaging Applications.Novel metal complexes of naphthalimide-cyclam conjugates as potential multi-target receptor tyrosine kinase (RTK) inhibitors: synthesis and biological evaluation.A highly sensitive long-wavelength fluorescence probe for nitroreductase and hypoxia: selective detection and quantification.7b, a novel naphthalimide derivative, exhibited anti-inflammatory effects via targeted-inhibiting TAK1 following down-regulation of ERK1/2- and p38 MAPK-mediated activation of NF-κB in LPS-stimulated RAW264.7 macrophages.Induction of apoptosis and suppression of ERCC1 expression by the potent amonafide analogue 8-c in human colorectal carcinoma cells.Oxo-heterocyclic fused naphthalimides as antitumor agents: synthesis and biological evaluation.7b, a novel amonafide analog, inhibited proliferation and phorbol 12-myristate 13-acetate/phytohemagglutinin-induced inflammatory responses of Jurkat T cells via p73-dependent pathway and decrease of nuclear factor-κB DNA-binding, respectively.Novel naphthalimide-benzoic acid conjugates as potential apoptosis-inducing agents: design, synthesis, and biological activity.Fluorescence properties and antiproliferative effects of mono-, bis-, and tris- thiophenylnaphthalimides: results of a comparative pilot study.Highly selective fluorescent probe for vicinal-dithiol-containing proteins and in situ imaging in living cells.A highly selective space-folded photo-induced electron transfer fluorescent probe for carbonic anhydrase isozymes IX and its applications for biological imaging.Acenaphtho[1,2-b]pyrrole-based selective fibroblast growth factor receptors 1 (FGFR1) inhibitors: design, synthesis, and biological activity.The novel anti-tumor agents of 4-triazol-1,8-naphthalimides: synthesis, cytotoxicity, DNA intercalation and photocleavage.7-b, a novel amonafide analogue, cause growth inhibition and apoptosis in Raji cells via a ROS-mediated mitochondrial pathway.
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Xuhong Qian
@ast
Xuhong Qian
@en
Xuhong Qian
@es
Xuhong Qian
@nl
Xuhong Qian
@sl
type
label
Xuhong Qian
@ast
Xuhong Qian
@en
Xuhong Qian
@es
Xuhong Qian
@nl
Xuhong Qian
@sl
prefLabel
Xuhong Qian
@ast
Xuhong Qian
@en
Xuhong Qian
@es
Xuhong Qian
@nl
Xuhong Qian
@sl
P106
P1153
7402052537
P31
P496
0000-0003-0394-1968