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DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 bindingIntersectin 1 forms a complex with adaptor protein Ruk/CIN85 in vivo independently of epidermal growth factor stimulationPhosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-lifeGenome-wide analysis of histidine repeats reveals their role in the localization of human proteins to the nuclear speckles compartmentThe molecular basis of glutamate formiminotransferase deficiencyStructural determinants of KvLQT1 control by the KCNE family of proteinsDyrk1A expression pattern supports specific roles of this kinase in the adult central nervous systemIntersectin 2, a new multimodular protein involved in clathrin-mediated endocytosis.Alu-splice cloning of human Intersectin (ITSN), a putative multivalent binding protein expressed in proliferating and differentiating neurons and overexpressed in Down syndrome.Integration of a growth-suppressing BTB/POZ domain protein with the DP component of the E2F transcription factor.A new aspartyl protease on 21q22.3, BACE2, is highly similar to Alzheimer's amyloid precursor protein beta-secretase.DYRK1A-mediated phosphorylation of GluN2A at Ser(1048) regulates the surface expression and channel activity of GluN1/GluN2A receptors.Individual expression of influenza virus PA protein induces degradation of coexpressed proteins.Key Role of Amino Acid Repeat Expansions in the Functional Diversification of Duplicated Transcription FactorsThe RCAN carboxyl end mediates calcineurin docking-dependent inhibition via a site that dictates binding to substrates and regulators.DYRK family of protein kinases: evolutionary relationships, biochemical properties, and functional roles.Chromatin-wide profiling of DYRK1A reveals a role as a gene-specific RNA polymerase II CTD kinase.Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protein, a translational activator of influenza virus.Cold shock induces the insertion of a cryptic exon in the neurofibromatosis type 1 (NF1) mRNASprouty2-mediated inhibition of fibroblast growth factor signaling is modulated by the protein kinase DYRK1A.Monoclonal antibodies against influenza virus PB2 and NP polypeptides interfere with the initiation step of viral mRNA synthesis in vitro.Resistance to foot-and-mouth disease virus mediated by trans-acting cellular products.Permanent cell lines that show temperature-dependent expression of adenovirus virus-associated RNA.Permanent cell lines established from ts-COS cells that regulate by temperature the amplification and expression of cloned genes.Regulation of gene amplification and expression in cells that constitutively express a temperature sensitive SV40 T-antigen.Mutational analysis of the influenza virus A/Victoria/3/75 PA protein: studies of interaction with PB1 protein and identification of a dominant negative mutant.Overexpression of tau protein in COS-1 cells results in the stabilization of centrosome-independent microtubules and extension of cytoplasmic processes.Influenza virus naked RNA can be expressed upon transfection into cells co-expressing the three subunits of the polymerase and the nucleoprotein from simian virus 40 recombinant viruses.Nuclear transport of influenza virus polymerase PA protein.pac gene as efficient dominant marker and reporter gene in mammalian cells.Splice variants of the dual specificity tyrosine phosphorylation-regulated kinase 4 (DYRK4) differ in their subcellular localization and catalytic activity.Construction of cell lines that regulate by temperature the amplification and expression of influenza virus non-structural protein genes.Characterization of a mouse model overexpressing beta-site APP-cleaving enzyme 2 reveals a new role for BACE2.The protein kinase DYRK1A regulates caspase-9-mediated apoptosis during retina development.DYRK1A accumulates in splicing speckles through a novel targeting signal and induces speckle disassembly.Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin.Influenza virus NS1 protein interacts with viral transcription-replication complexes in vivo.Epitope mapping of cross-reactive monoclonal antibodies specific for the influenza A virus PA and PB2 polypeptides.Complex structure of the nuclear translocation signal of influenza virus polymerase PA subunit.Synthesis of biologically active influenza virus core proteins using a vaccinia virus-T7 RNA polymerase expression system.
P50
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P50
description
hulumtuese
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researcher
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wetenschapper
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հետազոտող
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name
Susana de la Luna
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Susana de la Luna
@en
Susana de la Luna
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Susana de la Luna
@nl
Susana de la Luna
@sl
type
label
Susana de la Luna
@ast
Susana de la Luna
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Susana de la Luna
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Susana de la Luna
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Susana de la Luna
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altLabel
de la Luna S
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prefLabel
Susana de la Luna
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Susana de la Luna
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Susana de la Luna
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Susana de la Luna
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Susana de la Luna
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P1053
E-9553-2015
P106
P21
P31
P3829
P496
0000-0001-7765-916X