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Structural basis for different phosphoinositide specificities of the PX domains of sorting nexins regulating G-protein signalingStructural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteinsBinding partners for the COOH-terminal appendage domains of the GGAs and gamma-adaptinReconciling the regulatory role of Munc18 proteins in SNARE-complex assemblyPhosphoinositide binding by the SNX27 FERM domain regulates its localization at the immune synapse of activated T-cells.Crystal structure of a heptameric Sm-like protein complex from archaea: implications for the structure and evolution of snRNPsHomomeric ring assemblies of eukaryotic Sm proteins have affinity for both RNA and DNA. Crystal structure of an oligomeric complex of yeast SmFThe structure of the GGA1-GAT domain reveals the molecular basis for ARF binding and membrane association of GGAsStructural basis for binding of accessory proteins by the appendage domain of GGAsGamma-COP appendage domain - structure and functionA SNARE-adaptor interaction is a new mode of cargo recognition in clathrin-coated vesiclesStructure of Vps26B and mapping of its interaction with the retromer protein complexFragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitorsAssembly and solution structure of the core retromer protein complexStructural and thermodynamic analysis of the GFP:GFP-nanobody complexPossible roles for Munc18-1 domain 3a and Syntaxin1 N-peptide and C-terminal anchor in SNARE complex formationPhox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPasesQuantitative Analysis of Prenylated RhoA Interaction with Its Chaperone, RhoGDIStructural insights into the organization of the cavin membrane coat complexA molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complexParkinson Disease-linked Vps35 R524W Mutation Impairs the Endosomal Association of Retromer and Induces α-Synuclein AggregationVps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assemblyVPS29 is not an active metallo-phosphatase but is a rigid scaffold required for retromer interaction with accessory proteinsStructure and Membrane Binding Properties of the Endosomal Tetratricopeptide Repeat (TPR) Domain-containing Sorting Nexins SNX20 and SNX21Vps26A and Vps26B subunits define distinct retromer complexesStructure-based reassessment of the caveolin signaling model: do caveolae regulate signaling through caveolin-protein interactions?A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer.Rapid mapping of interactions between Human SNX-BAR proteins measured in vitro by AlphaScreen and single-molecule spectroscopy.Applications of isothermal titration calorimetry in pure and applied research--survey of the literature from 2010.Low-resolution solution structures of Munc18:Syntaxin protein complexes indicate an open binding mode driven by the Syntaxin N-peptide.Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling.Cavin family proteins and the assembly of caveolae.Unraveling the architecture of caveolaeThe structure and function of the retromer protein complex.Milligram quantities of homogeneous recombinant full-length mouse Munc18c from Escherichia coli cultures.Munc18-1 domain-1 controls vesicle docking and secretion by interacting with syntaxin-1 and chaperoning it to the plasma membraneAdaptors for clathrin coats: structure and function.Molecular Characterization of Caveolin-induced Membrane Curvature.A phosphoinositide-binding cluster in cavin1 acts as a molecular sensor for cavin1 degradation.Sorting nexin 27 couples PTHR trafficking to retromer for signal regulation in osteoblasts during bone growth.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Brett M Collins
@nl
Brett M Collins
@sl
Brett M. Collins
@en
Brett M. Collins
@es
type
label
Brett M Collins
@nl
Brett M Collins
@sl
Brett M. Collins
@en
Brett M. Collins
@es
prefLabel
Brett M Collins
@nl
Brett M Collins
@sl
Brett M. Collins
@en
Brett M. Collins
@es
P1053
J-1563-2014
P106
P1153
7201876024
P21
P31
P3829
P496
0000-0002-6070-3774