Mitochondrial respiratory chain complexes: apoptosis sensors mutated in cancer?
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The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenaseRegulation of SOD2 in cancer by histone modifications and CpG methylation: closing the loop between redox biology and epigeneticsUbiquinone-binding site mutagenesis reveals the role of mitochondrial complex II in cell death initiationAlterations in cellular energy metabolism associated with the antiproliferative effects of the ATM inhibitor KU-55933 and with metforminAlterations in c-Myc phenotypes resulting from dynamin-related protein 1 (Drp1)-mediated mitochondrial fission.Peroxisome proliferator-activated receptor gamma coactivator-1 alpha acts as a tumor suppressor in hepatocellular carcinoma.SOD1, an unexpected novel target for cancer therapyCoexpression within Integrated Mitochondrial Pathways Reveals Different Networks in Normal and Chemically Treated Transcriptomes.Endothelial cell metabolism: parallels and divergences with cancer cell metabolismProteomic study reveals a functional network of cancer markers in the G1-Stage of the breast cancer cell cycleA role for human mitochondrial complex II in the production of reactive oxygen species in human skinIdentification and analysis of multi-protein complexes in placenta.TIGAR is correlated with maximal standardized uptake value on FDG-PET and survival in non-small cell lung cancer.Dichloroacetate restores drug sensitivity in paclitaxel-resistant cells by inducing citric acid accumulation.Manganese superoxide dismutase: guardian of the powerhouse.PLGA-Loaded Gold-Nanoparticles Precipitated with Quercetin Downregulate HDAC-Akt Activities Controlling Proliferation and Activate p53-ROS Crosstalk to Induce Apoptosis in Hepatocarcinoma Cells.Subcellular localization and activity of gambogic acidThe transcriptional consequences of somatic amplifications, deletions, and rearrangements in a human lung squamous cell carcinomaActivating oxidative phosphorylation by a pyruvate dehydrogenase kinase inhibitor overcomes sorafenib resistance of hepatocellular carcinoma.Monoallelic loss of tumor suppressor GRIM-19 promotes tumorigenesis in mice.Quercetin induces mitochondrial biogenesis through activation of HO-1 in HepG2 cellsMetabolic remodelling in obesity and type 2 diabetes: pathological or protective mechanisms in response to nutrient excess?The mitochondrial permeability transition pore and its adaptive responses in tumor cells.Mitochondrial Respiration in Human Colorectal and Breast Cancer Clinical Material Is Regulated Differently.Evaluation of mitochondrial respiratory function in highly glycolytic glioma cells reveals low ADP phosphorylation in relation to oxidative capacity.Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has anti-oxidant and anti-apoptotic effects on tumor cells.α-Mangostin suppresses human gastric adenocarcinoma cells in vitro via blockade of Stat3 signaling pathway.Deficiency of the complex I of the mitochondrial respiratory chain but improved adenylate control over succinate-dependent respiration are human gastric cancer-specific phenomena.Mitochondria in chronic obstructive pulmonary disease and lung cancer: where are we now?Widening the concept of oncogeneCondurango-glycoside-A fraction of Gonolobus condurango induces DNA damage associated senescence and apoptosis via ROS-dependent p53 signalling pathway in HeLa cells.Cell Cycle Model System for Advancing Cancer Biomarker Research.From discovery of the CHOP axis and targeting ClpP to the identification of additional axes of the UPRmt driven by the estrogen receptor and SIRT3.The Role for Myc in Coordinating Glycolysis, Oxidative Phosphorylation, Glutaminolysis, and Fatty Acid Metabolism in Normal and Neoplastic Tissues.
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Mitochondrial respiratory chain complexes: apoptosis sensors mutated in cancer?
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 30 May 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Mitochondrial respiratory chain complexes: apoptosis sensors mutated in cancer?
@en
Mitochondrial respiratory chain complexes: apoptosis sensors mutated in cancer?
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type
label
Mitochondrial respiratory chain complexes: apoptosis sensors mutated in cancer?
@en
Mitochondrial respiratory chain complexes: apoptosis sensors mutated in cancer?
@nl
prefLabel
Mitochondrial respiratory chain complexes: apoptosis sensors mutated in cancer?
@en
Mitochondrial respiratory chain complexes: apoptosis sensors mutated in cancer?
@nl
P2860
P356
P1433
P1476
Mitochondrial respiratory chain complexes: apoptosis sensors mutated in cancer?
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P2093
P2860
P2888
P304
P356
10.1038/ONC.2011.167
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P577
2011-05-30T00:00:00Z