Similar interactions of natural products with biosynthetic enzymes and therapeutic targets could explain why nature produces such a large proportion of existing drugs.

Similar interactions of natural products with biosynthetic enzymes and therapeutic targets could explain why nature produces such a large proportion of existing drugs.

Item
http://www.wikidata.org/entity/Q37903716
The natural product magnolol as a lead structure for the development of potent cannabinoid receptor agonistsTotal synthesis of thiaplakortone a: derivatives as metabolically stable leads for the treatment of malaria.Design and synthesis of screening libraries based on the muurolane natural product scaffold.Identification of the first inhibitor of the GBP1:PIM1 interaction. Implications for the development of a new class of anticancer agents against paclitaxel resistant cancer cells.Construction of a natural product library containing secondary metabolites produced by actinomycetes.Endophytic Streptomyces sp. Y3111 from traditional Chinese medicine produced antitubercular pluramycins.Library construction and biological evaluation of enmein-type diterpenoid analogues as potential anticancer agents.Four new chloro-eremophilane sesquiterpenes from an Antarctic deep-sea derived fungus, Penicillium sp. PR19N-1Biodiscovery from rare actinomycetes: an eco-taxonomical perspective.Predicting natural product value, an exploration of anti-TB drug space.Design and synthesis of analogues of natural products.NMR fingerprints of the drug-like natural-product space identify iotrochotazine A: a chemical probe to study Parkinson's disease.Chemical Proteomics Identifies SLC25A20 as a Functional Target of the Ingenol Class of Actinic Keratosis Drugs.
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Similar interactions of natural products with biosynthetic enzymes and therapeutic targets could explain why nature produces such a large proportion of existing drugs.

Item
http://www.wikidata.org/entity/Q37903716
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 22 July 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Similar interactions of natura ...... proportion of existing drugs.
@en
Similar interactions of natura ...... proportion of existing drugs.
@nl
type
label
Similar interactions of natura ...... proportion of existing drugs.
@en
Similar interactions of natura ...... proportion of existing drugs.
@nl
prefLabel
Similar interactions of natura ...... proportion of existing drugs.
@en
Similar interactions of natura ...... proportion of existing drugs.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
Similar interactions of natura ...... proportion of existing drugs.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698