The maintenance of cytochrome P-450 in rat hepatocyte culture: some applications of liver cell cultures to the study of drug metabolism, toxicity and the induction of the P-450 system.
about
Transactivation Assays to Assess Canine and Rodent Pregnane X Receptor (PXR) and Constitutive Androstane Receptor (CAR) ActivationDifferential sensitivity of rat hepatocyte CYP isoforms to self-generated nitric oxide.miR-194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells in miceImplications and consequences of enzyme induction on preclinical and clinical drug development.Liver cell models in in vitro toxicology.Microengineered cell and tissue systems for drug screening and toxicology applications: Evolution of in-vitro liver technologies.Phenobarbital induction of cytochrome P-450 gene expression.Regulation of cytochrome P450 gene expression in human colon and breast tumour xenograftsThe cytochrome P450 gene superfamily.Effect of prototypical inducers on ligand activated nuclear receptor regulated drug disposition genes in rodent hepatic and intestinal cells.Manipulation of the phenotype of immortalised rat hepatocytes by different culture configurations and by dimethyl sulphoxide.Cytotoxicity of bile in human Hep G2 cells and in primary cultures of rat hepatocytes.Time for a consistent approach to preparing and culturing hepatocytes?Maintenance of total cytochrome P-450 content in rat hepatocyte culture and the abundance of CYP1A2 and CYP2B1/2 mRNAs.The effects of mebendazole on P4501A activity in rat hepatocytes and HepG2 cells. Comparison with tiabendazole and omeprazole.Disruption of endogenous regulator homeostasis underlies the mechanism of rat CYP1A1 mRNA induction by metyrapone.Importance of P450 reductase activity in determining sensitivity of breast tumour cells to the bioreductive drug, tirapazamine (SR 4233).Effects of various medium formulations and attachment substrata on the performance of cultured ruminant hepatocytes in biotransformation studies.Proline is required for transcriptional control of the aromatic hydrocarbon-inducible P(1)450 gene in C57BL/6 mouse monolayer-cultured hepatocytes.Phenobarbital induction of CYP1A1 gene expression in a primary culture of rainbow trout hepatocytes.Temperature-sensitive mRNA degradation is an early event in hepatocyte de-differentiation.Influence of verapamil on the efflux and metabolism of 14C moxidectin in cultured rat hepatocytes.Role of endogenous nitric oxide in liver-specific functions and survival of cultured rat hepatocytes.Itraconazole- and fluconazole-induced toxicity in rat hepatocytes: a comparative in vitro study.CYP isoform induction screening in 96-well plates: use of 7-benzyloxy-4-trifluoromethylcoumarin as a substrate for studies with rat hepatocytes.Effects of ethanol and clofibrate on expression of cytochrome P-450 enzymes and epoxide hydrolase in cultures and cocultures of rat hepatocytes.Suppression of intestinal and hepatic cytochrome P4503A in murine Toxoplasma infection. Effects of N-acetylcysteine and N(G)-monomethyl-L-arginine on the hepatic suppression.Induction of cytochrome P450 3A by retinoids in rat hepatocyte culture.Cryopreservation of rat hepatocyte monolayer cultures.Activation of Cyp1a1 and Cyp1a2 genes in adult mouse hepatocytes in primary culture.
P2860
Q28554648-04E4B91E-FE46-4149-8B2E-16C5CAC045F4Q31864614-49B13866-D88D-4A56-8704-DED729E9B33BQ34146018-8ECB73B0-B342-4F11-BAFC-CFBD17678EC4Q34378928-0C4D3A78-274C-46CC-AE01-0AFC4DA7D837Q34941510-8C28531B-0E15-40E7-8CF5-01F304894FB5Q35826421-266398E9-BA1B-43F1-BD33-284994E12D15Q35887158-D5677AAB-6B8C-4FA8-AE3E-4BB977064DD2Q35976231-26E17141-C2FA-4924-A152-C5B01271A0F0Q36028605-EF1D15D4-21CC-4BC1-939B-A6ED3123A52AQ37728687-91010A34-13C3-427B-AE9D-5EFF285D50DFQ40864802-B9E62038-2AFF-4567-87F6-32A74FFCAA63Q40999848-CD9D335B-E386-4D13-B05F-AAF56D62CE0AQ41147497-4C704377-017E-4E63-BA07-A8C5C1DDC1EBQ41835564-FA19A20B-3F04-4292-BEEC-4DF398126478Q42166558-4892F306-BB79-45DC-AA66-7B3253FAB465Q42176420-ACC1F835-535F-4420-89CE-FACDE6CB8CF8Q42261948-6B210E30-B025-4F08-B49E-517C82449F22Q42455954-774A2CEC-3D2A-4D16-9402-73F35703AD33Q42473037-28D21DFE-6F92-42C8-A441-01697EA870B9Q42555939-4D1F0371-3659-4FA3-BF5A-E33107A7C56CQ42988916-C78743EE-1440-4956-B8F6-8D161FD97FFAQ43666163-465CF2C1-D775-41C0-BE36-1B6BB4BF752DQ43699653-9B7C4DB1-4E84-4B9E-ADE9-5985BC5F54FDQ44015814-D88CE21B-C6F7-4DFF-A7E3-DA501D5E55E2Q44722298-A849B479-D3F3-4649-886A-CAAA13626D4AQ45243234-A9CFE2EC-179A-4E7D-97C3-FC8E529D4F2AQ45949638-37C60114-488D-437E-A808-F62C29D93273Q48051537-7FD55034-EF97-4834-BEBB-5804BCDD6447Q50754179-B6CFC5DF-6A75-452E-B057-3479449B72BDQ55240238-BBA26A5E-033C-4A61-8FF7-E1551A12B613
P2860
The maintenance of cytochrome P-450 in rat hepatocyte culture: some applications of liver cell cultures to the study of drug metabolism, toxicity and the induction of the P-450 system.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
The maintenance of cytochrome ...... induction of the P-450 system.
@en
The maintenance of cytochrome ...... induction of the P-450 system.
@nl
type
label
The maintenance of cytochrome ...... induction of the P-450 system.
@en
The maintenance of cytochrome ...... induction of the P-450 system.
@nl
prefLabel
The maintenance of cytochrome ...... induction of the P-450 system.
@en
The maintenance of cytochrome ...... induction of the P-450 system.
@nl
P1476
The maintenance of cytochrome ...... induction of the P-450 system.
@en
P2093
P356
10.1016/0009-2797(90)90055-R
P577
1990-01-01T00:00:00Z