The matriptase-prostasin proteolytic cascade in epithelial development and pathology.
about
Gene expression correlations in human cancer cell lines define molecular interaction networks for epithelial phenotypeDistinct roles of N-glycosylation at different sites of corin in cell membrane targeting and ectodomain shedding.The host microenvironment influences prostate cancer invasion, systemic spread, bone colonization, and osteoblastic metastasis.Exploiting PI3K/mTOR signaling to accelerate epithelial wound healing.Prostasin is required for matriptase activation in intestinal epithelial cells to regulate closure of the paracellular pathway.High Hepsin expression predicts poor prognosis in Gastric Cancer.Matriptase-mediated cleavage of EpCAM destabilizes claudins and dysregulates intestinal epithelial homeostasis.The Transmembrane Serine Protease HAT-like 4 Is Important for Epidermal Barrier Function to Prevent Body Fluid Loss.A Nonsense Variant in the ST14 Gene in Akhal-Teke Horses with Naked Foal Syndrome.Epidermal barriersDeregulated matriptase activity in oral squamous cell carcinoma promotes the infiltration of cancer-associated fibroblasts by paracrine activation of protease-activated receptor 2.The serine protease-mediated increase in intestinal epithelial barrier function is dependent on occludin and requires an intact tight junction.Down-regulation of HAI-1 is associated with poor-differentiation status of colorectal cancer.Current insights into protease dynamics in human epithelial disease and barrier function.Expression of matriptase correlates with tumour progression and clinical prognosis in oral squamous cell carcinoma.Changing the selectivity profile - from substrate analog inhibitors of thrombin and factor Xa to potent matriptase inhibitors.Matriptase, Protease-activated Receptor 2, and Idiopathic Pulmonary Fibrosis. Further Evidence for Signaling Pathway Redundancy in this Difficult-to-Treat Disease?Loss of HAI-2 in mice with decreased prostasin activity leads to an early-onset intestinal failure resembling congenital tufting enteropathy.
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The matriptase-prostasin proteolytic cascade in epithelial development and pathology.
description
article científic
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article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
The matriptase-prostasin proteolytic cascade in epithelial development and pathology.
@en
The matriptase-prostasin proteolytic cascade in epithelial development and pathology.
@nl
type
label
The matriptase-prostasin proteolytic cascade in epithelial development and pathology.
@en
The matriptase-prostasin proteolytic cascade in epithelial development and pathology.
@nl
prefLabel
The matriptase-prostasin proteolytic cascade in epithelial development and pathology.
@en
The matriptase-prostasin proteolytic cascade in epithelial development and pathology.
@nl
P2860
P1476
The matriptase-prostasin proteolytic cascade in epithelial development and pathology.
@en
P2093
Gregory S Miller
Karin List
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P2888
P304
P356
10.1007/S00441-012-1348-1
P577
2012-02-18T00:00:00Z