Targeting intracellular and extracellular alpha-synuclein as a therapeutic strategy in Parkinson's disease and other synucleinopathies.
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Reduced Risk of Parkinson's Disease in Users of Calcium Channel Blockers: A Meta-AnalysisAlpha-synuclein biology in Lewy body diseasesMultifunctional D2/D3 agonist D-520 with high in vivo efficacy: modulator of toxicity of alpha-synuclein aggregatesAnti-human α-synuclein N-terminal peptide antibody protects against dopaminergic cell death and ameliorates behavioral deficits in an AAV-α-synuclein rat model of Parkinson's disease.Constructing Structure Ensembles of Intrinsically Disordered Proteins from Chemical Shift Data.Altered Expression Patterns of Inflammation-Associated and Trophic Molecules in Substantia Nigra and Striatum Brain Samples from Parkinson's Disease, Incidental Lewy Body Disease and Normal Control Cases.Melatonin attenuates MPTP-induced neurotoxicity via preventing CDK5-mediated autophagy and SNCA/α-synuclein aggregation.Over-expression of an inactive mutant cathepsin D increases endogenous alpha-synuclein and cathepsin B activity in SH-SY5Y cells.Immunotherapy for neurodegenerative diseases: focus on α-synucleinopathies.Molecular basis of etiological implications in Alzheimer's disease: focus on neuroinflammation.Extracellular α--synuclein-a novel and crucial factor in Lewy body diseases.Protein Transmission, Seeding and Degradation: Key Steps for α-Synuclein Prion-Like PropagationA30P α-Synuclein interferes with the stable integration of adult-born neurons into the olfactory network.Is Parkinson's disease truly a prion-like disorder? An appraisal of current evidence.Targeting α-synuclein as a therapeutic strategy for Parkinson's disease.α-Synuclein aggregation modulation: an emerging approach for the treatment of Parkinson's disease.Development of Passive Immunotherapies for Synucleinopathies.A Molecular Tweezer Ameliorates Motor Deficits in Mice Overexpressing α-Synuclein.Iron and dopamine: a toxic couple.Impairment of chaperone-mediated autophagy induces dopaminergic neurodegeneration in rats.Valproic Acid Regulates α-Synuclein Expression through JNK Pathway in Rat Primary AstrocytesExtracellular alpha-synuclein induces calpain-dependent overactivation of cyclin-dependent kinase 5 in vitro.Low-Intensity Ultrasound Decreases α-Synuclein Aggregation via Attenuation of Mitochondrial Reactive Oxygen Species in MPP(+)-Treated PC12 Cells.Conformational Ensembles of α-Synuclein Derived Peptide with Different Osmolytes from Temperature Replica Exchange Sampling.Anti-MAG autoantibodies are increased in Parkinson's disease but not in atypical parkinsonism.Abundant fish protein inhibits α-synuclein amyloid formation.Tubulin and Tau: Possible targets for diagnosis of Parkinson's and Alzheimer's diseases.Anodal transcranial direct current stimulation prevents methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity by modulating autophagy in an in vivo mouse model of Parkinson's disease
P2860
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P2860
Targeting intracellular and extracellular alpha-synuclein as a therapeutic strategy in Parkinson's disease and other synucleinopathies.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Targeting intracellular and ex ...... e and other synucleinopathies.
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type
label
Targeting intracellular and ex ...... e and other synucleinopathies.
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prefLabel
Targeting intracellular and ex ...... e and other synucleinopathies.
@en
P2860
P1476
Targeting intracellular and ex ...... e and other synucleinopathies.
@en
P2093
Kostas Vekrellis
Leonidas Stefanis
P2860
P304
P356
10.1517/14728222.2012.674111
P407
P577
2012-04-01T00:00:00Z