Applications of asymmetric organocatalysis in medicinal chemistry.
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The ever-expanding role of asymmetric covalent organocatalysis in scalable, natural product synthesis.2,2',2''-Terpyridine-catalyzed synthesis of cyclic carbonates from epoxides and carbon dioxide under solvent-free conditionsEnantiomeric separation of biaryl atropisomers using cyclofructan based chiral stationary phases.Chiral hypervalent iodine reagents: synthesis and reactivity.Synergy, compatibility, and innovation: merging Lewis acids with stereoselective enamine catalysis.Asymmetric organocatalysis at the service of medicinal chemistryAsymmetric Michael Addition Organocatalyzed by α,β-Dipeptides under Solvent-Free Reaction Conditions.Catalysts Encapsulated in Molecular Machines.Dienamine and Friedel-Crafts one-pot synthesis, and antitumor evaluation of diheteroarylalkanals.Recent Advances in Asymmetric Organocatalyzed Conjugate Additions to Nitroalkenes.Design of Selenium-Based Chiral Chemical Probes for Simultaneous Enantio- and Chemosensing of Chiral Carboxylic Acids with Remote Stereogenic Centers by NMR Spectroscopy.Gold(I)-Mediated Thiourea Organocatalyst Activation: A Synergic Effect for Asymmetric Catalysis.Aromatic "Redox Tag"-assisted Diels-Alder reactions by electrocatalysis.Old tricks, new dogs: organocatalytic dienamine activation of α,β-unsaturated aldehydesOrganocatalytic 1,4-conjugate addition of ascorbic acid to α,β-unsaturated aldehydes: bio-inspired total syntheses of leucodrin, leudrin and proposed structure of dilaspirolactone.Enantioselective organocatalytic Michael additions of N,N'-dialkylbarbituric acids to enones.Organocatalytic Friedel-Crafts Alkylation/Lactonization Reaction of Naphthols with 3-Trifluoroethylidene Oxindoles: The Asymmetric Synthesis of Dihydrocoumarins.Chiral organocatalysts based on lipopeptide micelles for aldol reactions in water.Chemo- and Stereoselective Cross Rauhut-Currier-Type Reaction of Tri-substituted Alkenes Containing Trifluoromethyl Groups.Michael addition of carbonyl compounds to nitroolefins under the catalysis of new pyrrolidine-based bifunctional organocatalysts.High-performance liquid chromatographic enantioseparation of N-aryl-thioureidoalkylphosphonates and thiourylenedi(alkylphosphonates) on polysaccharide-based chiral stationary phases.Jørgensen-Hayashi catalysts supported on poly(ethylene glycol)s as highly efficient and reusable organocatalysts for the enamine-catalyzed asymmetric Michael reaction.Hydrogen-Bonding Network Promoted [3+2] Cycloaddition: Asymmetric Catalytic Construction of Spiro-pseudoindoxyl Derivatives.Organocatalyzed oxidative N-annulation for diverse and polyfunctionalized pyridines.γ'-Selective Functionalization of Cyclic Enones: Construction of a Chiral Quaternary Carbon Center by [4+2] Cycloaddition/Retro-Mannich Reaction with 3-Substituted Maleimides.NHC organocatalytic formal LUMO activation of α,β-unsaturated esters for reaction with enamides.Asymmetric aza-Morita-Baylis-Hillman reactions of chiral N-phosphonyl imines with acrylates via GAP chemistry/technology.Asymmetric and Site-Selective [3 + 2]-Annulations for the Synthesis of High-Value Bicyclic Lactams.A catalytic asymmetric hetero-Diels-Alder reaction of olefinic azlactones and isatins: facile access to chiral spirooxindole dihydropyranones.Catalyst-controlled regio- and stereoselective synthesis of diverse 12H-6,12-methanodibenzo[d,g][1,3]dioxocines.Chiral Responsive Liquid Quantum Dots.Drug design based on pentaerythritol tetranitrate reductase: synthesis and antibacterial activity of Pogostone derivatives.Investigations towards the stereoselective organocatalyzed Michael addition of dimethyl malonate to a racemic nitroalkene: possible route to the 4-methylpregabalin core structure.Core-Scaffold-Inspired Asymmetric Synthesis of Polysubstituted Chiral Hexahydropyridazines that Potently Inhibit Breast Cancer Cell Proliferation by Inducing Apoptosis.Oxadendralenes in asymmetric organocatalysis for the construction of tetrahydroisochromenes.A practical and stereoselective organocatalytic alkylation of aldehydes with benzodithiolylium tetrafluoroborateFacile preparation of a nanostructured functionalized catalytically active organosaltCinchona-Derived Picolinamides: Effective Organocatalysts for Stereoselective Imine Hydrosilylation
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Applications of asymmetric organocatalysis in medicinal chemistry.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Applications of asymmetric organocatalysis in medicinal chemistry.
@en
type
label
Applications of asymmetric organocatalysis in medicinal chemistry.
@en
prefLabel
Applications of asymmetric organocatalysis in medicinal chemistry.
@en
P2860
P356
P1476
Applications of asymmetric organocatalysis in medicinal chemistry.
@en
P2093
José Alemán
Silvia Cabrera
P2860
P304
P356
10.1039/C2CS35380F
P577
2013-01-01T00:00:00Z