Inherited cardiomyopathies caused by troponin mutations.
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The Importance of Intrinsically Disordered Segments of Cardiac Troponin in Modulating Function by Phosphorylation and Disease-Causing MutationsEffects of a myofilament calcium sensitizer on left ventricular systolic and diastolic function in rats with volume overload heart failureRat cardiac troponin T mutation (F72L)-mediated impact on thin filament cooperativity is divergently modulated by α- and β-myosin heavy chain isoforms.Identification of rare variants in TNNI3 with atrial fibrillation in a Chinese GeneID populationA Restrictive Cardiomyopathy Mutation in an Invariant Proline at the Myosin Head/Rod Junction Enhances Head Flexibility and Function, Yielding Muscle Defects in DrosophilaCardiac troponin T is necessary for normal development in the embryonic chick heart.Dilated Cardiomyopathy Mutation (R134W) in Mouse Cardiac Troponin T Induces Greater Contractile Deficits against α-Myosin Heavy Chain than against β-Myosin Heavy Chain.TNNT1, TNNT2, and TNNT3: Isoform genes, regulation, and structure-function relationships.Insights and Challenges of Multi-Scale Modeling of Sarcomere Mechanics in cTn and Tm DCM Mutants-Genotype to Cellular Phenotype.Determinants of myocardial conduction velocity: implications for arrhythmogenesis.Experimental models of inherited cardiomyopathy and its therapeutics.L71F mutation in rat cardiac troponin T augments crossbridge recruitment and detachment dynamics against α-myosin heavy chain, but not against β-myosin heavy chain.Cardiomyopathy-related mutation (A30V) in mouse cardiac troponin T divergently alters the magnitude of stretch activation in α- and β-myosin heavy chain fibers.Overview of the Muscle Cytoskeleton.Green Tea Catechin Normalizes the Enhanced Ca2+ Sensitivity of Myofilaments Regulated by a Hypertrophic Cardiomyopathy-Associated Mutation in Human Cardiac Troponin I (K206I)The effect of cardiomyopathy mutation (R97L) in mouse cardiac troponin T on the muscle length-mediated recruitment of crossbridges is modified divergently by α- and β-myosin heavy chain.Knock-in mice harboring a Ca(2+) desensitizing mutation in cardiac troponin C develop early onset dilated cardiomyopathy.Functional significance of C-terminal mobile domain of cardiac troponin I.Molecular mechanisms and structural features of cardiomyopathy-causing troponin T mutants in the tropomyosin overlap region.Multiple Species Comparison of Cardiac Troponin T and Dystrophin: Unravelling the DNA behind Dilated Cardiomyopathy.Troponin through the looking-glass: emerging roles beyond regulation of striated muscle contraction.PRKACA phosphorylates TNNI3Genetic and Tissue Engineering Approaches to Modeling the Mechanics of Human Heart Failure for Drug Discovery
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Inherited cardiomyopathies caused by troponin mutations.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artículo científico
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Inherited cardiomyopathies caused by troponin mutations.
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type
label
Inherited cardiomyopathies caused by troponin mutations.
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prefLabel
Inherited cardiomyopathies caused by troponin mutations.
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P1476
Inherited cardiomyopathies caused by troponin mutations
@en
P2093
Qun-Wei Lu
Xiao-Yan Wu
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P304
P356
10.3969/J.ISSN.1671-5411.2013.01.014
P577
2013-03-01T00:00:00Z