The molecular and structural basis of advanced antiviral therapy for hepatitis C virus infection.
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Recent Advances in Antiviral Therapy for Chronic Hepatitis CRecent advances in managing chronic HCV infection: focus on therapy in patients with severe liver diseaseAnimal models for the study of HCVThe yin and yang of hepatitis C: synthesis and decay of hepatitis C virus RNAFinally sofosbuvir: an oral anti-HCV drug with wide performance capabilityProspects for nucleic acid-based therapeutics against hepatitis C virusNovel approaches and challenges to treatment of central nervous system viral infectionsEmerging therapies for the treatment of hepatitis CViruses in cancer cell plasticity: the role of hepatitis C virus in hepatocellular carcinomaAsymmetric binding to NS5A by daclatasvir (BMS-790052) and analogs suggests two novel modes of HCV inhibition.A Single-Cell Platform for Monitoring Viral Proteolytic Cleavage in Different Cellular CompartmentsTRIM14 inhibits hepatitis C virus infection by SPRY domain-dependent targeted degradation of the viral NS5A proteinDevelopment of a rapid phenotypic test for HCV protease inhibitors with potential use in clinical decisionsDiscovery of a novel series of potent non-nucleoside inhibitors of hepatitis C virus NS5B.NS2 Proteins of GB Virus B and Hepatitis C Virus Share Common Protease Activities and Membrane TopologiesStructural and Thermodynamic Effects of Macrocyclization in HCV NS3/4A Inhibitor MK-5172Hepatitis C virus: Virology, diagnosis and treatmentInterferon-free combination therapies for the treatment of hepatitis C: current insightsElucidating novel hepatitis C virus-host interactions using combined mass spectrometry and functional genomics approachesHepatitis C virus RNA replication depends on specific cis- and trans-acting activities of viral nonstructural proteinsMultiple Introduction and Naturally Occuring Drug Resistance of HCV among HIV-Infected Intravenous Drug Users in Yunnan: An Origin of China's HIV/HCV EpidemicsGeno2pheno[HCV] - A Web-based Interpretation System to Support Hepatitis C Treatment Decisions in the Era of Direct-Acting Antiviral AgentsC-Terminal Auto-Regulatory Motif of Hepatitis C Virus NS5B Interacts with Human VAPB-MSP to Form a Dynamic Replication ComplexAnalysis of serine codon conservation reveals diverse phenotypic constraints on hepatitis C virus glycoprotein evolutionBiophysical Mode-of-Action and Selectivity Analysis of Allosteric Inhibitors of Hepatitis C Virus (HCV) Polymerase.Long-term functional duration of immune responses to HCV NS3/4A induced by DNA vaccination.Selective inhibition of hepatitis C virus infection by hydroxyzine and benztropine.The combination of alisporivir plus an NS5A inhibitor provides additive to synergistic anti-hepatitis C virus activity without detectable cross-resistance.Determinants for membrane association of the hepatitis C virus NS2 protease domain.Aryl-substituted aminobenzimidazoles targeting the hepatitis C virus internal ribosome entry site.Transcriptional suppression of miR-181c by hepatitis C virus enhances homeobox A1 expression.Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation.Autophagy in HCV infection: keeping fat and inflammation at bayImmune control and failure in HCV infection--tipping the balance.Hepatitis C virus NS5A inhibitors and drug resistance mutations.Systematic review: current concepts and challenges for the direct-acting antiviral era in hepatitis C cirrhosis.Cross-genotypic examination of hepatitis C virus polymerase inhibitors reveals a novel mechanism of action for thumb bindersIntrinsic disorder mediates hepatitis C virus core-host cell protein interactions.Effect of sofosbuvir and ribavirin treatment on peripheral and hepatic lipid metabolism in chronic hepatitis C virus, genotype 1-infected patients.Nonstructural protein 5A (NS5A) and human replication protein A increase the processivity of hepatitis C virus NS5B polymerase activity in vitro.
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P2860
The molecular and structural basis of advanced antiviral therapy for hepatitis C virus infection.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
The molecular and structural b ...... r hepatitis C virus infection.
@en
type
label
The molecular and structural b ...... r hepatitis C virus infection.
@en
prefLabel
The molecular and structural b ...... r hepatitis C virus infection.
@en
P2860
P356
P1476
The molecular and structural b ...... r hepatitis C virus infection.
@en
P2093
Francois Penin
P2860
P2888
P304
P356
10.1038/NRMICRO3046
P407
P577
2013-06-10T00:00:00Z
P5875
P6179
1028226528